diff --git a/sci-libs/indilib/indilib-1.9.2.ebuild b/sci-libs/indilib/indilib-1.9.2.ebuild
index f5901ff88e0ff..d1a9b7106bd03 100644
--- a/sci-libs/indilib/indilib-1.9.2.ebuild
+++ b/sci-libs/indilib/indilib-1.9.2.ebuild
@@ -53,5 +53,17 @@ src_configure() {
 }
 
 src_test() {
+	local myctestargs=()
+
+	if use ppc || use ppc64 || use sparc ; then
+		# Broken on big endian for quite some time.
+		# Reported upstream: file needs to be replaced w/ a normal library
+		# for b64.
+		# bug #763126
+		myctestargs+=(
+			-E "(test_base64)"
+		)
+	fi
+
 	BUILD_DIR="${BUILD_DIR}"/test cmake_src_test
 }