diff --git a/dev-python/blosc/Manifest b/dev-python/blosc/Manifest
index ea85fd0824220..3e4bd98e47ad2 100644
--- a/dev-python/blosc/Manifest
+++ b/dev-python/blosc/Manifest
@@ -1,2 +1 @@
-DIST python-blosc-1.10.5.gh.tar.gz 1570462 BLAKE2B e2ee3cc3827e1df89afc97a0cdc3f07670368d2edfea9b6ae32ecbb74b464d5311bbd7b129b3b94fb91d20fd579425859412665de397facd4c119e429fbcd014 SHA512 75b91e50def65ecbbdd29f7b7aba65c6ca611eeeaa9e55583c0253eda5d1e1ab7d899d0c77c45ae999188f701205f20d8c8ed130a3865433edd87db3c0eeebb0
 DIST python-blosc-1.10.6.gh.tar.gz 1570504 BLAKE2B 44f444fa5050a6198e83649973fc82d6804eec50bf79c332ed6a974e417f2a58baf09480a9bb5c5b7abcef2a961cd7bc61f962c12db625b1a7c48799ace0b39a SHA512 e283b132ebb91e7ce362ec65a1d6760e3793046371ea545a9e842372084182bcc194c3a0e1cb20914de58554063995a238ea0a129214731689e8cd5f4203d3ed
diff --git a/dev-python/blosc/blosc-1.10.5-r1.ebuild b/dev-python/blosc/blosc-1.10.5-r1.ebuild
deleted file mode 100644
index 79ef5a1ac1426..0000000000000
--- a/dev-python/blosc/blosc-1.10.5-r1.ebuild
+++ /dev/null
@@ -1,44 +0,0 @@
-# Copyright 1999-2022 Gentoo Authors
-# Distributed under the terms of the GNU General Public License v2
-
-EAPI=8
-
-DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{8..10} )
-
-inherit distutils-r1
-
-MY_P=python-blosc-${PV}
-DESCRIPTION="High performance compressor optimized for binary data"
-HOMEPAGE="http://python-blosc.blosc.org"
-SRC_URI="
-	https://github.com/Blosc/python-blosc/archive/v${PV}.tar.gz
-		-> ${MY_P}.gh.tar.gz
-"
-S=${WORKDIR}/${MY_P}
-
-SLOT="0"
-LICENSE="MIT"
-KEYWORDS="amd64 arm arm64 ~hppa ~ia64 ppc ppc64 ~riscv ~s390 ~sparc x86 ~amd64-linux ~x86-linux"
-IUSE="test"
-RESTRICT="!test? ( test )"
-
-RDEPEND=">=dev-libs/c-blosc-1.19.0:="
-DEPEND="${RDEPEND}"
-BDEPEND="
-	dev-python/scikit-build[${PYTHON_USEDEP}]
-	test? (
-		dev-python/numpy[${PYTHON_USEDEP}]
-	)
-"
-
-DOCS=( ANNOUNCE.rst README.rst RELEASE_NOTES.rst )
-
-src_configure() {
-	export USE_SYSTEM_BLOSC=1
-	export BLOSC_DIR="${EPREFIX}/usr"
-}
-
-python_test() {
-	"${EPYTHON}" -m blosc.test -v || die
-}