diff --git a/dev-python/indexed-gzip/Manifest b/dev-python/indexed-gzip/Manifest
index 57c71f05add7..1c7607c5c0d0 100644
--- a/dev-python/indexed-gzip/Manifest
+++ b/dev-python/indexed-gzip/Manifest
@@ -1 +1,2 @@
 DIST indexed_gzip-1.10.1.tar.gz 267180 BLAKE2B 0ee462826424ba1fd920969355d976167a9278b0a247493dc4d79510101a7b14a8db056fe329f3d6fb2ac40ab08e783b1f3e638a172555b8e3b70122576d8405 SHA512 950317796adc125d2ed22573b573d98fcbaefed1d973126f7fb886575f8413338041d0f28027de2265434b54d2fffe32107c52d52ad6d19c0a0087f10824eac1
+DIST indexed_gzip-1.10.3.tar.gz 275900 BLAKE2B 7c65a6351a368222262ea56f09b193971959a3a5a56e7e8c949b47c76b2f7a96056f925f795da1b4215cf63dc1f904e826bff0ac7e75c0b990e681f7d5609db7 SHA512 3b5a00ba004d43f4a5fa76d127df7136f1db227de5f294a4e128df8d7da64f7a16d9c4106dd92510a3528c7b66f27f59f2968830430c94f544ce9dd6c69699b5
diff --git a/dev-python/indexed-gzip/indexed-gzip-1.10.3.ebuild b/dev-python/indexed-gzip/indexed-gzip-1.10.3.ebuild
new file mode 100644
index 000000000000..7d440abe122d
--- /dev/null
+++ b/dev-python/indexed-gzip/indexed-gzip-1.10.3.ebuild
@@ -0,0 +1,62 @@
+# Copyright 1999-2025 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+DISTUTILS_EXT=1
+DISTUTILS_USE_PEP517=setuptools
+PYTHON_COMPAT=( python3_{11..14} )
+
+inherit distutils-r1 pypi
+
+DESCRIPTION="Fast random access of gzip files in Python"
+HOMEPAGE="
+	https://pypi.org/project/indexed-gzip/
+	https://github.com/pauldmccarthy/indexed_gzip/
+"
+
+LICENSE="ZLIB"
+SLOT="0"
+KEYWORDS="~amd64 ~x86"
+
+RDEPEND="
+	virtual/zlib:=
+"
+DEPEND="
+	${RDEPEND}
+"
+BDEPEND="
+	dev-python/cython[${PYTHON_USEDEP}]
+	dev-python/setuptools-scm[${PYTHON_USEDEP}]
+	test? (
+		dev-python/numpy[${PYTHON_USEDEP}]
+	)
+"
+
+EPYTEST_PLUGINS=()
+EPYTEST_XDIST=1
+distutils_enable_tests pytest
+
+src_compile() {
+	# This actually enables line tracing, so it fits USE=debug more.
+	if use debug; then
+		export INDEXED_GZIP_TESTING=1
+	fi
+	# Fix implicit dependency on numpy that is used to build test
+	# extensions.
+	if ! use test; then
+		local -x PYTHONPATH="${T}:${PYTHONPATH}"
+		cat >> "${T}"/numpy.py <<-EOF || die
+			raise ImportError("I am not here!")
+		EOF
+	fi
+	distutils-r1_src_compile
+}
+
+python_test() {
+	cd "${BUILD_DIR}/install$(python_get_sitedir)/indexed_gzip/tests" || die
+	epytest -m "not slow_test"
+	# temporary files and test extensions
+	# (to achieve equivalence with USE=-test)
+	rm ctest*.{c,gz,so,tmp} || die
+}