diff --git a/dev-python/libusb1/Manifest b/dev-python/libusb1/Manifest
index 10aaf932733f1..f468220ed99af 100644
--- a/dev-python/libusb1/Manifest
+++ b/dev-python/libusb1/Manifest
@@ -1 +1,2 @@
 DIST libusb1-3.2.0.tar.gz 105601 BLAKE2B 11a4f49253e3698448c97b9ede585d67f8c174fb0fdeb4040077f9851e96b4ffb50af4ee02fe9ca2b4c22f47098e5d1d3798aa34a2ed75f43dae23d8d96eec25 SHA512 5979d50e0f3fe6e0054bb67a13e1c7c31f9f468949ea51dccd9a990bf6e2333c35136e0f6fe46c66902f5c135872999a5657abc8b4205d8349704fa8b9f53759
+DIST libusb1-3.3.1.tar.gz 107600 BLAKE2B 7ec6a0fecc4f2c7520a7b8dc47d9000176ef3054b4171bac82f4c77824c62f2532346ef356dcd9b677ccac3a24f29913668a5be60c7c10b35ceca38f1eb7904c SHA512 a565130a81751b5927bb5c9023e3236314bbf9fbc5c3bbdd7ae21f45197bb545ad189af034e9f187ffe626659d2bf65a5ecb9d323c99837fbae0a7ff0dac99ce
diff --git a/dev-python/libusb1/libusb1-3.3.1.ebuild b/dev-python/libusb1/libusb1-3.3.1.ebuild
new file mode 100644
index 0000000000000..757b1d9b4d472
--- /dev/null
+++ b/dev-python/libusb1/libusb1-3.3.1.ebuild
@@ -0,0 +1,29 @@
+# Copyright 2025 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+DISTUTILS_USE_PEP517=setuptools
+PYTHON_COMPAT=( python3_{10..13} python3_13t )
+
+inherit distutils-r1
+
+DESCRIPTION="Python ctype-based wrapper around libusb1"
+HOMEPAGE="https://github.com/vpelletier/python-libusb1"
+SRC_URI="https://github.com/vpelletier/python-libusb1/releases/download/${PV}/${P}.tar.gz"
+
+LICENSE="LGPL-2.1+"
+SLOT="0"
+KEYWORDS="~amd64 ~arm64 ~x86"
+IUSE="test"
+
+RDEPEND="virtual/libusb:1"
+DEPEND="test? ( ${RDEPEND} )"
+
+distutils_enable_tests unittest
+
+src_prepare() {
+	# Don't need this.
+	rm -r usb1/__pyinstaller || die
+	default
+}