diff --git a/dev-python/pikepdf/pikepdf-8.11.2-r1.ebuild b/dev-python/pikepdf/pikepdf-8.11.2-r1.ebuild
index 417da5be9fcdf..bbd2842097b50 100644
--- a/dev-python/pikepdf/pikepdf-8.11.2-r1.ebuild
+++ b/dev-python/pikepdf/pikepdf-8.11.2-r1.ebuild
@@ -42,7 +42,6 @@ BDEPEND="
 		>=dev-python/psutil-5.9[${PYTHON_USEDEP}]
 		>=dev-python/pytest-timeout-2.1.0[${PYTHON_USEDEP}]
 		>=dev-python/python-dateutil-2.8.1[${PYTHON_USEDEP}]
-		>=dev-python/python-xmp-toolkit-2.0.1[${PYTHON_USEDEP}]
 		$(python_gen_cond_dep '
 			dev-python/tomli[${PYTHON_USEDEP}]
 		' 3.10)
diff --git a/dev-python/pikepdf/pikepdf-8.14.0-r1.ebuild b/dev-python/pikepdf/pikepdf-8.14.0-r1.ebuild
index 367e7b427436a..342767bd45fb3 100644
--- a/dev-python/pikepdf/pikepdf-8.14.0-r1.ebuild
+++ b/dev-python/pikepdf/pikepdf-8.14.0-r1.ebuild
@@ -42,7 +42,6 @@ BDEPEND="
 		>=dev-python/psutil-5.9[${PYTHON_USEDEP}]
 		>=dev-python/pytest-timeout-2.1.0[${PYTHON_USEDEP}]
 		>=dev-python/python-dateutil-2.8.1[${PYTHON_USEDEP}]
-		>=dev-python/python-xmp-toolkit-2.0.1[${PYTHON_USEDEP}]
 		$(python_gen_cond_dep '
 			dev-python/tomli[${PYTHON_USEDEP}]
 		' 3.10)
diff --git a/dev-python/pikepdf/pikepdf-8.15.1-r1.ebuild b/dev-python/pikepdf/pikepdf-8.15.1-r1.ebuild
index 367e7b427436a..5c93cf4933f1e 100644
--- a/dev-python/pikepdf/pikepdf-8.15.1-r1.ebuild
+++ b/dev-python/pikepdf/pikepdf-8.15.1-r1.ebuild
@@ -18,6 +18,7 @@ HOMEPAGE="
 LICENSE="MPL-2.0"
 SLOT="0"
 KEYWORDS="~alpha amd64 arm arm64 ~hppa ~ia64 ~loong ~ppc ppc64 ~riscv ~s390 sparc x86"
+IUSE="big-endian"
 
 # Check QPDF_MIN_VERSION in pyproject.toml on bumps, as well as
 # https://qpdf.readthedocs.io/en/stable/release-notes.html.
@@ -42,7 +43,9 @@ BDEPEND="
 		>=dev-python/psutil-5.9[${PYTHON_USEDEP}]
 		>=dev-python/pytest-timeout-2.1.0[${PYTHON_USEDEP}]
 		>=dev-python/python-dateutil-2.8.1[${PYTHON_USEDEP}]
-		>=dev-python/python-xmp-toolkit-2.0.1[${PYTHON_USEDEP}]
+		!big-endian? (
+			>=dev-python/python-xmp-toolkit-2.0.1[${PYTHON_USEDEP}]
+		)
 		$(python_gen_cond_dep '
 			dev-python/tomli[${PYTHON_USEDEP}]
 		' 3.10)
diff --git a/dev-python/pikepdf/pikepdf-8.4.1-r1.ebuild b/dev-python/pikepdf/pikepdf-8.4.1-r1.ebuild
index 74215529a0585..96db3b5989477 100644
--- a/dev-python/pikepdf/pikepdf-8.4.1-r1.ebuild
+++ b/dev-python/pikepdf/pikepdf-8.4.1-r1.ebuild
@@ -42,7 +42,6 @@ BDEPEND="
 		>=dev-python/psutil-5.9[${PYTHON_USEDEP}]
 		>=dev-python/pytest-timeout-2.1.0[${PYTHON_USEDEP}]
 		>=dev-python/python-dateutil-2.8.1[${PYTHON_USEDEP}]
-		>=dev-python/python-xmp-toolkit-2.0.1[${PYTHON_USEDEP}]
 		$(python_gen_cond_dep '
 			dev-python/tomli[${PYTHON_USEDEP}]
 		' 3.{8..10})
diff --git a/dev-python/pikepdf/pikepdf-9.0.0.ebuild b/dev-python/pikepdf/pikepdf-9.0.0.ebuild
index 420eaac097bfc..14d1f25d88bc6 100644
--- a/dev-python/pikepdf/pikepdf-9.0.0.ebuild
+++ b/dev-python/pikepdf/pikepdf-9.0.0.ebuild
@@ -18,6 +18,7 @@ HOMEPAGE="
 LICENSE="MPL-2.0"
 SLOT="0"
 KEYWORDS="~alpha ~amd64 ~arm ~arm64 ~hppa ~ia64 ~loong ~ppc ~ppc64 ~riscv ~s390 ~sparc ~x86"
+IUSE="big-endian"
 
 # Check QPDF_MIN_VERSION in pyproject.toml on bumps, as well as
 # https://qpdf.readthedocs.io/en/stable/release-notes.html.
@@ -42,7 +43,9 @@ BDEPEND="
 		>=dev-python/psutil-5.9[${PYTHON_USEDEP}]
 		>=dev-python/pytest-timeout-2.1.0[${PYTHON_USEDEP}]
 		>=dev-python/python-dateutil-2.8.1[${PYTHON_USEDEP}]
-		>=dev-python/python-xmp-toolkit-2.0.1[${PYTHON_USEDEP}]
+		!big-endian? (
+			>=dev-python/python-xmp-toolkit-2.0.1[${PYTHON_USEDEP}]
+		)
 		$(python_gen_cond_dep '
 			dev-python/tomli[${PYTHON_USEDEP}]
 		' 3.10)