diff --git a/dev-python/pyudev/pyudev-0.21.0.ebuild b/dev-python/pyudev/pyudev-0.21.0.ebuild
index ac3b0ab16602e..234a751f550ef 100644
--- a/dev-python/pyudev/pyudev-0.21.0.ebuild
+++ b/dev-python/pyudev/pyudev-0.21.0.ebuild
@@ -13,13 +13,12 @@ SRC_URI="mirror://pypi/${PN:0:1}/${PN}/${P}.tar.gz"
 LICENSE="LGPL-2.1"
 SLOT="0"
 KEYWORDS="~amd64 ~arm ~arm64 ~x86"
-IUSE="pygobject qt4 qt5 pyside test"
+IUSE="pygobject qt5 pyside test"
 REQUIRED_USE="pygobject? ( || ( $(python_gen_useflags 'python2*') ) )"
 
 RDEPEND="virtual/udev
 	dev-python/six[${PYTHON_USEDEP}]
 	pygobject? ( dev-python/pygobject:2[$(python_gen_usedep 'python2*')] )
-	qt4? ( dev-python/PyQt4[${PYTHON_USEDEP}] )
 	qt5? ( dev-python/PyQt5[${PYTHON_USEDEP}] )
 	pyside? ( dev-python/pyside[${PYTHON_USEDEP}] )"
 DEPEND="${RDEPEND}