diff --git a/sys-fs/zfs/zfs-2.1.0-r1.ebuild b/sys-fs/zfs/zfs-2.1.0-r1.ebuild
index 9f8ac5af22074..2ab356846cf34 100644
--- a/sys-fs/zfs/zfs-2.1.0-r1.ebuild
+++ b/sys-fs/zfs/zfs-2.1.0-r1.ebuild
@@ -54,6 +54,10 @@ BDEPEND="virtual/awk
 	nls? ( sys-devel/gettext )
 	python? (
 		dev-python/setuptools[${PYTHON_USEDEP}]
+		|| (
+			dev-python/packaging[${PYTHON_USEDEP}]
+			dev-python/distlib[${PYTHON_USEDEP}]
+		)
 	)
 "
 
diff --git a/sys-fs/zfs/zfs-2.1.1-r1.ebuild b/sys-fs/zfs/zfs-2.1.1-r1.ebuild
index e1514c972f16b..b18fbb2606140 100644
--- a/sys-fs/zfs/zfs-2.1.1-r1.ebuild
+++ b/sys-fs/zfs/zfs-2.1.1-r1.ebuild
@@ -180,7 +180,6 @@ src_configure() {
 	local myconf=(
 		--bindir="${EPREFIX}/bin"
 		--enable-shared
-		--enable-systemd
 		--enable-sysvinit
 		--localstatedir="${EPREFIX}/var"
 		--sbindir="${EPREFIX}/sbin"
@@ -194,6 +193,10 @@ src_configure() {
 		--with-systemdunitdir="$(systemd_get_systemunitdir)"
 		--with-systemdpresetdir="${EPREFIX}/lib/systemd/system-preset"
 		--with-vendor=gentoo
+		# Building zfs-mount-generator.c on musl breaks as strndupa
+		# isn't available. But systemd doesn't support musl anyway, so
+		# just disable building it.
+		$(use_enable !elibc_musl systemd)
 		$(use_enable debug)
 		$(use_enable nls)
 		$(use_enable pam)
diff --git a/sys-fs/zfs/zfs-9999.ebuild b/sys-fs/zfs/zfs-9999.ebuild
index 10db2b452cba2..43755044ed6b6 100644
--- a/sys-fs/zfs/zfs-9999.ebuild
+++ b/sys-fs/zfs/zfs-9999.ebuild
@@ -182,7 +182,6 @@ src_configure() {
 	local myconf=(
 		--bindir="${EPREFIX}/bin"
 		--enable-shared
-		--enable-systemd
 		--enable-sysvinit
 		--localstatedir="${EPREFIX}/var"
 		--sbindir="${EPREFIX}/sbin"
@@ -196,6 +195,10 @@ src_configure() {
 		--with-systemdunitdir="$(systemd_get_systemunitdir)"
 		--with-systemdpresetdir="${EPREFIX}/lib/systemd/system-preset"
 		--with-vendor=gentoo
+		# Building zfs-mount-generator.c on musl breaks as strndupa
+		# isn't available. But systemd doesn't support musl anyway, so
+		# just disable building it.
+		$(use_enable !elibc_musl systemd)
 		$(use_enable debug)
 		$(use_enable nls)
 		$(use_enable pam)