diff --git a/profiles/arch/amd64/no-multilib/package.use.mask b/profiles/arch/amd64/no-multilib/package.use.mask
index 4da2ef66274e9..45829472692de 100644
--- a/profiles/arch/amd64/no-multilib/package.use.mask
+++ b/profiles/arch/amd64/no-multilib/package.use.mask
@@ -1,6 +1,10 @@
 # Copyright 1999-2019 Gentoo Authors
 # Distributed under the terms of the GNU General Public License v2
 
+# Sam James <sam@gentoo.org> (2020-12-27)
+# dev-embedded/libftd2xx unavailable here
+dev-embedded/urjtag ftd2xx
+
 # Robin H. Johnson <robbat2@gentoo.org> (2019-12-06)
 # PPS should work on all arches, but only keyworded on some arches
 >=net-misc/ntp-4.2.6_p3-r1 -parse-clocks
diff --git a/profiles/arch/powerpc/package.use.mask b/profiles/arch/powerpc/package.use.mask
index 7a09b7b974d20..50f91db89b3e7 100644
--- a/profiles/arch/powerpc/package.use.mask
+++ b/profiles/arch/powerpc/package.use.mask
@@ -1,6 +1,10 @@
 # Copyright 1999-2020 Gentoo Authors
 # Distributed under the terms of the GNU General Public License v2
 
+# Sam James <sam@gentoo.org> (2020-12-27)
+# dev-embedded/libftd2xx unavailable here
+dev-embedded/urjtag ftd2xx
+
 # Georgy Yakovlev <gyakovlev@gentoo.org> (2020-11-05)
 # makes no sense on power
 sys-apps/fwupd amt dell uefi
diff --git a/profiles/arch/sparc/package.use.mask b/profiles/arch/sparc/package.use.mask
index a8e59a86d8e1c..cdf245730e3ff 100644
--- a/profiles/arch/sparc/package.use.mask
+++ b/profiles/arch/sparc/package.use.mask
@@ -1,6 +1,10 @@
 # Copyright 1999-2020 Gentoo Authors
 # Distributed under the terms of the GNU General Public License v2
 
+# Sam James <sam@gentoo.org> (2020-12-27)
+# dev-embedded/libftd2xx unavailable here
+dev-embedded/urjtag ftd2xx
+
 # Matthias Maier <tamiko@gentoo.org> (2020-12-03)
 # Requires sci-mathematics/z3.
 dev-util/cppcheck z3