diff --git a/dev-python/tox/tox-3.14.3.ebuild b/dev-python/tox/tox-3.14.3.ebuild
index e9ee49b58a243..e16af1d4b10f8 100644
--- a/dev-python/tox/tox-3.14.3.ebuild
+++ b/dev-python/tox/tox-3.14.3.ebuild
@@ -3,6 +3,7 @@
 
 EAPI=7
 
+DISTUTILS_USE_SETUPTOOLS=rdepend
 PYTHON_COMPAT=( python3_{6,7,8} pypy3 )
 
 inherit distutils-r1
@@ -28,7 +29,6 @@ RDEPEND="
 	<dev-python/pluggy-1.0[${PYTHON_USEDEP}]
 	dev-python/pip[${PYTHON_USEDEP}]
 	dev-python/py[${PYTHON_USEDEP}]
-	dev-python/setuptools[${PYTHON_USEDEP}]
 	dev-python/six[${PYTHON_USEDEP}]
 	dev-python/toml[${PYTHON_USEDEP}]
 	>=dev-python/virtualenv-16.0.0[${PYTHON_USEDEP}]"