diff --git a/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-5.7.1-r1.ebuild b/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-5.7.1-r1.ebuild
index 65314b8b6b380..ade2c6f349f66 100644
--- a/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-5.7.1-r1.ebuild
+++ b/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-5.7.1-r1.ebuild
@@ -48,6 +48,14 @@ OB		git-r3_checkout
 }
 
 src_configure() {
+	# -Werror=strict-aliasing
+	# https://bugs.gentoo.org/856088
+	# https://github.com/ROCm/clr/issues/64
+	#
+	# Do not trust it for LTO either
+	append-flags -fno-strict-aliasing
+	filter-lto
+
 	# Fix ld.lld linker error: https://github.com/RadeonOpenCompute/ROCm-OpenCL-Runtime/issues/155
 	append-ldflags $(test-flags-CCLD -Wl,--undefined-version)
 
diff --git a/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-6.0.0.ebuild b/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-6.0.0.ebuild
index 8a2b71872bdc5..b6912994ddb73 100644
--- a/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-6.0.0.ebuild
+++ b/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-6.0.0.ebuild
@@ -48,6 +48,14 @@ OB		git-r3_checkout
 }
 
 src_configure() {
+	# -Werror=strict-aliasing
+	# https://bugs.gentoo.org/856088
+	# https://github.com/ROCm/clr/issues/64
+	#
+	# Do not trust it for LTO either
+	append-flags -fno-strict-aliasing
+	filter-lto
+
 	# Fix ld.lld linker error: https://github.com/RadeonOpenCompute/ROCm-OpenCL-Runtime/issues/155
 	append-ldflags $(test-flags-CCLD -Wl,--undefined-version)
 
diff --git a/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-9999.ebuild b/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-9999.ebuild
index 878cf8bbc33d9..1ca30c8a10aeb 100644
--- a/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-9999.ebuild
+++ b/dev-libs/rocm-opencl-runtime/rocm-opencl-runtime-9999.ebuild
@@ -59,6 +59,14 @@ src_prepare() {
 }
 
 src_configure() {
+	# -Werror=strict-aliasing
+	# https://bugs.gentoo.org/856088
+	# https://github.com/ROCm/clr/issues/64
+	#
+	# Do not trust it for LTO either
+	append-flags -fno-strict-aliasing
+	filter-lto
+
 	# Fix ld.lld linker error: https://github.com/RadeonOpenCompute/ROCm-OpenCL-Runtime/issues/155
 	append-ldflags $(test-flags-CCLD -Wl,--undefined-version)