diff --git a/profiles/package.mask b/profiles/package.mask
index 011f574b9fe91..daf926af857fc 100644
--- a/profiles/package.mask
+++ b/profiles/package.mask
@@ -29,6 +29,11 @@
 
 #--- END OF EXAMPLES ---
 
+# Andreas Sturmlechner <asturm@gentoo.org> (08 Apr 2018)
+# Depends on dead Qt4. Use sci-chemistry/avogadro2 instead.
+# Masked for removal in 30 days. Bugs #645030
+sci-chemistry/avogadro
+
 # Jason Zaman <perfinion@gentoo.org> (08 Apr 2018)
 # Dead upstream, for an old version of Xfce
 # Masked for removal in 30 days.