diff --git a/dev-python/pyatspi/Manifest b/dev-python/pyatspi/Manifest
index 74f34d55d119c..e24e86a5dcc84 100644
--- a/dev-python/pyatspi/Manifest
+++ b/dev-python/pyatspi/Manifest
@@ -1,3 +1,2 @@
-DIST pyatspi-2.46.1.tar.xz 323392 BLAKE2B ee55f57616d58ead8bbf14193a984e2d268b0dafd67bdb638086fe531d7d031b6060f2c757036f67ad18ba6c1f774c8ef13a4844c5fb96878604f59903b2653a SHA512 69c1c4c31bef430083a1c9af98ba6b2f1b3d9eec0a5f03982b980838bcf86933069a90d7314d2e5501d5988a453d0a803ad239eca5b98f08cc3bf7dc8d4a7c0c
 DIST pyatspi-2.58.1.tar.xz 82620 BLAKE2B 1c96e56ebd274b3760f6b3568f03a98894d95c991356a16095b5a9ef3be73490347166aa0fb74abc5141c644eb20b5b94234fb43fb0fe2228f469e6a6e86c9bd SHA512 b1ad8baac2a3fde60f13399372813404ca3296d5a7036dd9896a3b0fe509353bc2b98b93abf42efa2e7ca703d416ec32a77118baeebbecbe962e99ef2a985dd8
 DIST pyatspi-2.58.2.tar.xz 82640 BLAKE2B 9b25ba8e6d78bc15b399d2b5507e6a0721dc4bb8899df9a1ae1fd2b415685b49f019bd9e6588f16b8e7f7dedc2d35f258f37544b55c38d0288c75ec242d23a82 SHA512 2e6fb18b3bd4bcad4ee25eb53cf4fade0030a1921a861e0a39c89a492dd382cd20071af93207033d9eaed59ae15319245e3e9221678aba5f8cf1790865057a9c
diff --git a/dev-python/pyatspi/pyatspi-2.46.1.ebuild b/dev-python/pyatspi/pyatspi-2.46.1.ebuild
deleted file mode 100644
index 85254f27dfac5..0000000000000
--- a/dev-python/pyatspi/pyatspi-2.46.1.ebuild
+++ /dev/null
@@ -1,65 +0,0 @@
-# Copyright 1999-2025 Gentoo Authors
-# Distributed under the terms of the GNU General Public License v2
-
-EAPI=8
-PYTHON_COMPAT=( python3_{10..13} )
-
-inherit gnome2 python-r1
-
-DESCRIPTION="Python client bindings for D-Bus AT-SPI"
-HOMEPAGE="https://wiki.gnome.org/Accessibility"
-
-# Note: only some of the tests are GPL-licensed, everything else is LGPL
-LICENSE="LGPL-2 GPL-2+"
-SLOT="0"
-KEYWORDS="~alpha amd64 ~arm arm64 ~hppa ~loong ~ppc ~ppc64 ~riscv ~sparc x86"
-
-IUSE="test"
-RESTRICT="!test? ( test )"
-REQUIRED_USE="${PYTHON_REQUIRED_USE}"
-
-DEPEND="
-	${PYTHON_DEPS}
-	>=dev-libs/atk-2.11.2
-	dev-python/dbus-python[${PYTHON_USEDEP}]
-	>=dev-python/pygobject-2.90.1:3[${PYTHON_USEDEP}]
-"
-RDEPEND="
-	${DEPEND}
-	>=sys-apps/dbus-1
-	>=app-accessibility/at-spi2-core-2.34[introspection]
-"
-# sys-apps/which BDEPEND can be dropped on next release (>2.46.1)
-BDEPEND="
-	sys-apps/which
-	virtual/pkgconfig
-	test? ( x11-libs/gtk+:3 )
-"
-
-src_prepare() {
-	gnome2_src_prepare
-	python_copy_sources
-}
-
-src_configure() {
-	python_foreach_impl run_in_build_dir gnome2_src_configure $(use_enable test tests)
-}
-
-src_compile() {
-	python_foreach_impl run_in_build_dir gnome2_src_compile
-}
-
-src_test() {
-	python_foreach_impl run_in_build_dir dbus-run-session emake check
-}
-
-src_install() {
-	installing() {
-		gnome2_src_install
-		python_optimize
-	}
-	python_foreach_impl run_in_build_dir installing
-
-	docinto examples
-	dodoc examples/*.py
-}