diff --git a/dev-python/h2/Manifest b/dev-python/h2/Manifest
index 33ef6e0747bfc..d54c669d7be30 100644
--- a/dev-python/h2/Manifest
+++ b/dev-python/h2/Manifest
@@ -1,3 +1,2 @@
 DIST h2-4.1.0.tar.gz 2143812 BLAKE2B b9d9a771340b4bde1675b9fd65c242732a1a262456f84a409662cf2b57326e24e0583160ba0531c0b105b79342578714127dddb560d2a27de58af34d1052c698 SHA512 4e9cf88b3ae702a8a42bded775ad337809787fe8172d501c230d55abbf1edd764acf3b227f2e58756d882499661ffcf6bbdd4812a4d938c04fac3f1aa2390b28
 DIST hyper-h2-3.2.0.tar.gz 2203333 BLAKE2B 245bab162852070e850613c41162c75efe5e43535945dacf448afdc948cade83402f77259aa46f375d0772a5287e42d8842b1259cb36392cc8fc222dec7cef75 SHA512 103a4ea2cd29037ce03ae676864125b4111c7d31a82bbbe7028557da886d88fb5363d885f08d5d3f68dfa29013b7b03350cc0cb4d9dddf32735e98dae5d7fc7c
-DIST hyper-h2-4.0.0.tar.gz 2142185 BLAKE2B e5ae692c1f21b6e3ea8695ec269a4d02f72b8d385b6f9c523775f3db2200379f9af5accb70fa06a357575728a6a5b2644dd1225cfdf458fffa80e84c7b1c7b2f SHA512 84578174a13782897f9286c62d450eaf11aa71c01c96b8660179cd2df77618dc1a6c4b354b2bc5731cd21c4709c8c0a8282a859a98c4a62a7295b6dfd1b5cfb2
diff --git a/dev-python/h2/h2-4.0.0.ebuild b/dev-python/h2/h2-4.0.0.ebuild
deleted file mode 100644
index 410e17cd3adb1..0000000000000
--- a/dev-python/h2/h2-4.0.0.ebuild
+++ /dev/null
@@ -1,52 +0,0 @@
-# Copyright 1999-2021 Gentoo Authors
-# Distributed under the terms of the GNU General Public License v2
-
-EAPI=7
-
-PYTHON_COMPAT=( python3_{8..10} )
-inherit distutils-r1
-
-MY_P=hyper-h2-${PV}
-DESCRIPTION="HTTP/2 State-Machine based protocol implementation"
-HOMEPAGE="https://python-hyper.org/h2/en/stable/ https://pypi.org/project/h2/"
-SRC_URI="https://github.com/python-hyper/${PN}/archive/v${PV}.tar.gz -> ${MY_P}.tar.gz"
-S=${WORKDIR}/${MY_P}
-
-LICENSE="MIT"
-SLOT="0"
-KEYWORDS="~alpha amd64 arm arm64 hppa ~ia64 ~mips ppc ppc64 ~riscv ~s390 sparc x86"
-
-RDEPEND="
-	>=dev-python/hyperframe-6.0[${PYTHON_USEDEP}]
-	<dev-python/hyperframe-7[${PYTHON_USEDEP}]
-	>=dev-python/hpack-4.0[${PYTHON_USEDEP}]
-	<dev-python/hpack-5[${PYTHON_USEDEP}]
-"
-BDEPEND="
-	test? (
-		dev-python/hypothesis[${PYTHON_USEDEP}]
-	)
-"
-
-distutils_enable_tests pytest
-
-PATCHES=(
-	# From https://github.com/python-hyper/h2/pull/1248
-	# Disables some failing healthchecks
-	"${FILESDIR}/hyper-h2-3.2.0-failed-healthcheck.patch"
-)
-
-python_test() {
-	local deselect=()
-	[[ ${EPYTHON} == python3.10 ]] && deselect+=(
-		# these rely on fixed string repr() and fail because enum repr
-		# changed in py3.10
-		test/test_basic_logic.py::TestBasicServer::test_stream_repr
-		test/test_events.py::TestEventReprs::test_remotesettingschanged_repr
-		test/test_events.py::TestEventReprs::test_streamreset_repr
-		test/test_events.py::TestEventReprs::test_settingsacknowledged_repr
-		test/test_events.py::TestEventReprs::test_connectionterminated_repr
-	)
-
-	epytest ${deselect[@]/#/--deselect }
-}