diff --git a/dev-python/grpcio-tools/Manifest b/dev-python/grpcio-tools/Manifest
index cefbb8ad8db2a..ee91d0cef1c98 100644
--- a/dev-python/grpcio-tools/Manifest
+++ b/dev-python/grpcio-tools/Manifest
@@ -1 +1,2 @@
 DIST grpcio-tools-1.41.1.tar.gz 2173046 BLAKE2B 2edfda68c5e5eaa86a69f2061d1b13a6c7070ad4152a20ecea910d4685e0face957aa204c639e4e72b04c131bccca63549a83aa38f0e5201304b48352e4ae3ab SHA512 8f9ea6c2541670cb206059c378b33425fea3d63c3e890ba064581e780dcd3b0ce5f9c890731cac35d14281bfa49182857148fe2794a9373914493c4e0d4ce3b9
+DIST grpcio-tools-1.43.0.tar.gz 2210483 BLAKE2B 5daab31940dc5a21fbfea0985f6056361375be1b45f1a00e9345dc25808050193e20c9316d2a2a18d9a5f503787506f6d76a3bdf95ac6b3b7525873076b9d1e0 SHA512 60a5fa62fc1a81b5a57b47aca212ed94913ca20c3c1055dac18101776177fc0b18cc480c7356332e3eb4cf7819634ddc53d2e77f7c4b582a0fa53e26053f3ed4
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.43.0.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.43.0.ebuild
new file mode 100644
index 0000000000000..e37b353978289
--- /dev/null
+++ b/dev-python/grpcio-tools/grpcio-tools-1.43.0.ebuild
@@ -0,0 +1,35 @@
+# Copyright 1999-2021 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=7
+
+DISTUTILS_USE_SETUPTOOLS=rdepend
+PYTHON_COMPAT=( python3_{8..10} )
+
+inherit distutils-r1 multiprocessing prefix
+
+DESCRIPTION="Protobuf code generator for gRPC"
+HOMEPAGE="https://grpc.io"
+SRC_URI="mirror://pypi/${PN::1}/${PN}/${P}.tar.gz"
+
+LICENSE="Apache-2.0"
+SLOT="0"
+KEYWORDS="~amd64 ~arm64 ~ppc64 ~x86"
+
+RDEPEND="
+	dev-python/cython[${PYTHON_USEDEP}]
+	~dev-python/grpcio-${PV}[${PYTHON_USEDEP}]
+	dev-python/protobuf-python[${PYTHON_USEDEP}]
+"
+
+DEPEND="${RDEPEND}"
+
+python_prepare_all() {
+	distutils-r1_python_prepare_all
+	hprefixify setup.py
+}
+
+python_configure_all() {
+	export GRPC_PYTHON_BUILD_WITH_CYTHON=1
+	export GRPC_PYTHON_BUILD_EXT_COMPILER_JOBS="$(makeopts_jobs)"
+}