diff --git a/dev-libs/rocr-runtime/Manifest b/dev-libs/rocr-runtime/Manifest
index dc4ec59783042..b4df296c78504 100644
--- a/dev-libs/rocr-runtime/Manifest
+++ b/dev-libs/rocr-runtime/Manifest
@@ -5,4 +5,4 @@ DIST rocr-runtime-5.5.1.tar.gz 816175 BLAKE2B e588d98cbd0d9a753b950ba676d6cddeed
 DIST rocr-runtime-5.7.1.tar.gz 832009 BLAKE2B 67e4a64ee03b1f6edc43923c7ac44113ab58f78b032dc0a01952b2dd5b2ca37404044811effb9c8d83002ac4ea344a5d95ac62f3c66012bff2884ef55285cdb5 SHA512 a6547a104303032244d17b662a3eda48039732c215debb6178c0af8842c01c60f80989793420c101bd554e58332d215205da0c228dfc25538c56499f47dc6832
 DIST rocr-runtime-6.1.1.tar.gz 903611 BLAKE2B 175e7267bfd9d70fb805135e765004cf2b43b2d66354f0cef857d417c8dac4ce7638ec1b90a1088324aa5f90ed8354c66b56846115368d68d622a215350d84dd SHA512 5e6e28dee29ef9df9d617f56038b2e52022738d5510833cd8e1738defe1049d0a957db4d9f63bbf55d8efca3a4ea349b95919dd1b6b35b9814ebba575a67af57
 DIST rocr-runtime-6.1.2.tar.gz 903633 BLAKE2B 058492c6c37bb80e8cdb29752f3f1404ac88108dcfd5137042e4fdaff521db01d64bd14bdcbed9e53b8984f8bbb22b126f1a798bd064c393b5bcf76c1d3311ca SHA512 2893aff72a5fbf03bfde67ab64fcf00f4e10b5e5b11ff4617e94ae0c019a24a9b80601d8629d4e119e6a4957dc0aaf03d645111063979af60090fe3b232a477e
-DIST rocr-runtime-6.2.4.tar.gz 959982 BLAKE2B a4cc3960c7e559c7c1837e009c998784832c861ca59c0cbf9388c8ae081670b4e45c4e5b032dbd17a4c2efe8708a1330c9ff66c814196e29df5c7a6735a6d3e9 SHA512 cdd84ddf2120f494eec282b78d0858970e0603ea096213f25731af5a97f652d058ff93122bb3a0813c45cb87f625af6f33c2c108d8fb5db63d62674b13e40c71
+DIST rocr-runtime-6.3.0.tar.gz 2258605 BLAKE2B 53b43a8bc4a327c2138e39db20f5217b2def6866d1b52e48017c41e6c3c8541e6bdce76f5a7669cdffccfb34a4cfa863e56e0ce4058d23c5f38d9d0900903751 SHA512 451e74d88875b8d0a1f21d95c543fd93610d966e69258b50fe4b8796381c58f5ea381384e199e5bcf01a80369a59e5a093d8f318fbe2ed1ca6a97dc915060f7a
diff --git a/dev-libs/rocr-runtime/files/rocr-runtime-6.2.0-ld-lld.patch b/dev-libs/rocr-runtime/files/rocr-runtime-6.2.0-ld-lld.patch
new file mode 100644
index 0000000000000..e35ee8c0e46ba
--- /dev/null
+++ b/dev-libs/rocr-runtime/files/rocr-runtime-6.2.0-ld-lld.patch
@@ -0,0 +1,17 @@
+Fix "symbol not defined" when linking with ld.lld >= 17
+https://github.com/ROCm/ROCR-Runtime/issues/204
+--- a/hsacore.so.def
++++ b/hsacore.so.def
+@@ -247,12 +247,6 @@ global:
+ 	hsa_amd_vmem_retain_alloc_handle;
+ 	hsa_amd_vmem_get_alloc_properties_from_handle;
+ 	hsa_amd_agent_set_async_scratch_limit;
+-	hsa_tools_scratch_event_alloc_start;
+-	hsa_tools_scratch_event_alloc_end;
+-	hsa_tools_scratch_event_free_start;
+-	hsa_tools_scratch_event_free_end;
+-	hsa_tools_scratch_event_async_reclaim_start;
+-	hsa_tools_scratch_event_async_reclaim_end;
+ 	hsa_ven_amd_pcs_iterate_configuration;
+ 	hsa_ven_amd_pcs_create;
+ 	hsa_ven_amd_pcs_create_from_id;
diff --git a/dev-libs/rocr-runtime/files/rocr-runtime-6.2.0-no-aqlprofiler.patch b/dev-libs/rocr-runtime/files/rocr-runtime-6.2.0-no-aqlprofiler.patch
new file mode 100644
index 0000000000000..018c3298ed8dc
--- /dev/null
+++ b/dev-libs/rocr-runtime/files/rocr-runtime-6.2.0-no-aqlprofiler.patch
@@ -0,0 +1,27 @@
+libhsa-amd-aqlprofile64 library is not packaged
+Bug: https://github.com/ROCm/ROCm/issues/1781
+--- a/core/runtime/amd_gpu_agent.cpp
++++ b/core/runtime/amd_gpu_agent.cpp
+@@ -1333,11 +1333,6 @@ hsa_status_t GpuAgent::GetInfo(hsa_agent_info_t attribute, void* value) const {
+         setFlag(HSA_EXTENSION_AMD_PC_SAMPLING);
+       }
+ 
+-      if (os::LibHandle lib = os::LoadLib(kAqlProfileLib)) {
+-        os::CloseLib(lib);
+-        setFlag(HSA_EXTENSION_AMD_AQLPROFILE);
+-      }
+-
+       setFlag(HSA_EXTENSION_AMD_PROFILER);
+ 
+       break;
+--- a/core/runtime/hsa.cpp
++++ b/core/runtime/hsa.cpp
+@@ -490,7 +490,7 @@ hsa_status_t hsa_system_get_major_extension_table(uint16_t extension, uint16_t v
+     return HSA_STATUS_SUCCESS;
+   }
+ 
+-  if (extension == HSA_EXTENSION_AMD_AQLPROFILE) {
++  if (0) {
+     if (version_major != hsa_ven_amd_aqlprofile_VERSION_MAJOR) {
+       debug_print("aqlprofile API incompatible ver %d, current ver %d\n",
+         version_major, hsa_ven_amd_aqlprofile_VERSION_MAJOR);
diff --git a/dev-libs/rocr-runtime/files/rocr-runtime-6.2.2-gcc15-stdint.patch b/dev-libs/rocr-runtime/files/rocr-runtime-6.2.2-gcc15-stdint.patch
new file mode 100644
index 0000000000000..21691ae0c1c08
--- /dev/null
+++ b/dev-libs/rocr-runtime/files/rocr-runtime-6.2.2-gcc15-stdint.patch
@@ -0,0 +1,11 @@
+https://github.com/ROCm/ROCR-Runtime/issues/227
+--- a/core/inc/amd_elf_image.hpp
++++ b/core/inc/amd_elf_image.hpp
+@@ -47,6 +47,7 @@
+ #include <sstream>
+ #include <vector>
+ #include <memory>
++#include <cstdint>
+ 
+ namespace rocr {
+ namespace amd {
diff --git a/dev-libs/rocr-runtime/files/rocr-runtime-6.3.0-musl.patch b/dev-libs/rocr-runtime/files/rocr-runtime-6.3.0-musl.patch
new file mode 100644
index 0000000000000..75cd032ce3735
--- /dev/null
+++ b/dev-libs/rocr-runtime/files/rocr-runtime-6.3.0-musl.patch
@@ -0,0 +1,107 @@
+--- a/runtime/hsa-ext-finalize/CMakeLists.txt
++++ b/runtime/hsa-ext-finalize/CMakeLists.txt
+@@ -101,6 +101,18 @@ if( NOT DEFINED OPEN_SOURCE_DIR )
+   set ( OPEN_SOURCE_DIR "${CMAKE_CURRENT_SOURCE_DIR}/.." )
+ endif()
+ 
++## Check for _GNU_SOURCE pthread extensions
++set(CMAKE_REQUIRED_DEFINITIONS -D_GNU_SOURCE)
++CHECK_SYMBOL_EXISTS ( "pthread_attr_setaffinity_np" "pthread.h" HAVE_PTHREAD_ATTR_SETAFFINITY_NP )
++CHECK_SYMBOL_EXISTS ( "pthread_rwlockattr_setkind_np" "pthread.h" HAVE_PTHREAD_RWLOCKATTR_SETKIND_NP )
++unset(CMAKE_REQUIRED_DEFINITIONS)
++if ( HAVE_PTHREAD_ATTR_SETAFFINITY_NP )
++  target_compile_definitions(${CORE_RUNTIME_TARGET} PRIVATE HAVE_PTHREAD_ATTR_SETAFFINITY_NP )
++endif()
++if ( HAVE_PTHREAD_RWLOCKATTR_SETKIND_NP )
++  target_compile_definitions(${CORE_RUNTIME_TARGET} PRIVATE HAVE_PTHREAD_RWLOCKATTR_SETKIND_NP )
++endif()
++
+ ## ------------------------- Linux Compiler and Linker options -------------------------
+ set ( CMAKE_CXX_FLAGS "-std=c++11 " )
+ 
+--- a/runtime/hsa-runtime/CMakeLists.txt
++++ b/runtime/hsa-runtime/CMakeLists.txt
+@@ -47,7 +47,7 @@ cmake_minimum_required ( VERSION 3.7 )
+ ## Need an update to CMake 3.12 to remove this hack. See CMake policy change CMP0073.
+ unset ( hsa-runtime64_LIB_DEPENDS CACHE )
+ 
+-set(CMAKE_VERBOSE_MAKEFILE ON)
++#_cmake_modify_IGNORE set(CMAKE_VERBOSE_MAKEFILE ON)
+ 
+ ## Set core runtime module name and project name.
+ set ( CORE_RUNTIME_NAME "hsa-runtime64" )
+@@ -109,6 +109,18 @@ if ( HAVE_MEMFD_CREATE )
+   target_compile_definitions(${CORE_RUNTIME_TARGET} PRIVATE HAVE_MEMFD_CREATE )
+ endif()
+ 
++## Check for _GNU_SOURCE pthread extensions
++set(CMAKE_REQUIRED_DEFINITIONS -D_GNU_SOURCE)
++CHECK_SYMBOL_EXISTS ( "pthread_attr_setaffinity_np" "pthread.h" HAVE_PTHREAD_ATTR_SETAFFINITY_NP )
++CHECK_SYMBOL_EXISTS ( "pthread_rwlockattr_setkind_np" "pthread.h" HAVE_PTHREAD_RWLOCKATTR_SETKIND_NP )
++unset(CMAKE_REQUIRED_DEFINITIONS)
++if ( HAVE_PTHREAD_ATTR_SETAFFINITY_NP )
++  target_compile_definitions(${CORE_RUNTIME_TARGET} PRIVATE HAVE_PTHREAD_ATTR_SETAFFINITY_NP )
++endif()
++if ( HAVE_PTHREAD_RWLOCKATTR_SETKIND_NP )
++  target_compile_definitions(${CORE_RUNTIME_TARGET} PRIVATE HAVE_PTHREAD_RWLOCKATTR_SETKIND_NP )
++endif()
++
+ ## Set include directories for ROCr runtime
+ target_include_directories( ${CORE_RUNTIME_TARGET}
+   PUBLIC
+--- a/runtime/hsa-runtime/core/util/lnx/os_linux.cpp
++++ b/runtime/hsa-runtime/core/util/lnx/os_linux.cpp
+@@ -137,12 +137,14 @@ class os_thread {
+       for (int i = 0; i < cores; i++) {
+         CPU_SET_S(i, CPU_ALLOC_SIZE(cores), cpuset);
+       }
++#ifdef HAVE_PTHREAD_ATTR_SETAFFINITY_NP
+       err = pthread_attr_setaffinity_np(&attrib, CPU_ALLOC_SIZE(cores), cpuset);
+       CPU_FREE(cpuset);
+       if (err != 0) {
+         fprintf(stderr, "pthread_setaffinity_np failed: %s\n", strerror(err));
+         return;
+       }
++#endif
+     }
+ 
+     do {
+@@ -165,6 +167,18 @@ class os_thread {
+       }
+     } while (stackSize < 20 * 1024 * 1024);
+ 
++#ifndef HAVE_PTHREAD_ATTR_SETAFFINITY_NP
++    if (cores && cpuset) {
++      err = pthread_setaffinity_np(thread, CPU_ALLOC_SIZE(cores), cpuset);
++      CPU_FREE(cpuset);
++      if (err != 0) {
++        fprintf(stderr, "pthread_setaffinity_np failed: %s\n", strerror(err));
++        thread = 0;
++        return;
++      }
++    }
++#endif
++
+     args.release();
+   }
+ 
+@@ -655,18 +669,12 @@ SharedMutex CreateSharedMutex() {
+     return nullptr;
+   }
+ 
+-#ifdef __GLIBC__
++#ifdef HAVE_PTHREAD_RWLOCKATTR_SETKIND_NP
+   err = pthread_rwlockattr_setkind_np(&attrib, PTHREAD_RWLOCK_PREFER_WRITER_NONRECURSIVE_NP);
+   if (err != 0) {
+     fprintf(stderr, "Set rw lock attribute failure: %s\n", strerror(err));
+     return nullptr;
+   }
+-#else
+-  err = pthread_rwlockattr_setkind(&attrib, PTHREAD_RWLOCK_PREFER_WRITER_NONRECURSIVE_NP);
+-  if (err != 0) {
+-    fprintf(stderr, "Set rw lock attribute failure: %s\n", strerror(err));
+-    return nullptr;
+-  }
+ #endif
+ 
+   pthread_rwlock_t* lock = new pthread_rwlock_t;
diff --git a/dev-libs/rocr-runtime/files/rocr-runtime-6.3.0-use-system-hsakmt.patch b/dev-libs/rocr-runtime/files/rocr-runtime-6.3.0-use-system-hsakmt.patch
new file mode 100644
index 0000000000000..06f6610a71f46
--- /dev/null
+++ b/dev-libs/rocr-runtime/files/rocr-runtime-6.3.0-use-system-hsakmt.patch
@@ -0,0 +1,20 @@
+libhsakmt is a part of dev-libs/roct-thunk-interface
+--- a/CMakeLists.txt
++++ b/CMakeLists.txt
+@@ -96,11 +96,16 @@ if (HSA_DEP_ROCPROFILER_REGISTER)
+   string(APPEND CPACK_RPM_BINARY_PACKAGE_REQUIRES " rocprofiler-register")
+ endif()
+ 
++if (BUILD_HSAKMT)
+ add_rocm_subdir(libhsakmt "${THUNK_DEFINITIONS}")
+ set_target_properties(hsakmt PROPERTIES
+                                 ARCHIVE_OUTPUT_DIRECTORY "${CMAKE_CURRENT_BINARY_DIR}/libhsakmt/archive"
+                                 LIBRARY_OUTPUT_DIRECTORY "${CMAKE_CURRENT_BINARY_DIR}/libhsakmt/lib"
+                                 RUNTIME_OUTPUT_DIRECTORY "${CMAKE_CURRENT_BINARY_DIR}/libhsakmt/runtime")
++else()
++  find_package(hsakmt REQUIRED)
++  add_library(hsakmt ALIAS hsakmt::hsakmt)
++endif()
+ 
+ if (BUILD_ROCR)
+   add_rocm_subdir(runtime/hsa-runtime "${ROCR_DEFINITIONS}")
diff --git a/dev-libs/rocr-runtime/rocr-runtime-6.1.2.ebuild b/dev-libs/rocr-runtime/rocr-runtime-6.1.2.ebuild
index d7000ea9ca923..4caff8c750f22 100644
--- a/dev-libs/rocr-runtime/rocr-runtime-6.1.2.ebuild
+++ b/dev-libs/rocr-runtime/rocr-runtime-6.1.2.ebuild
@@ -33,8 +33,8 @@ IUSE="debug"
 COMMON_DEPEND="dev-libs/elfutils
 	x11-libs/libdrm"
 DEPEND="${COMMON_DEPEND}
-	>=dev-libs/roct-thunk-interface-${PV}
-	>=dev-libs/rocm-device-libs-${PV}
+	dev-libs/roct-thunk-interface:${SLOT}
+	dev-libs/rocm-device-libs:${SLOT}
 	$(llvm_gen_dep '
 		llvm-core/clang:${LLVM_SLOT}=
 		llvm-core/lld:${LLVM_SLOT}=
diff --git a/dev-libs/rocr-runtime/rocr-runtime-6.2.4.ebuild b/dev-libs/rocr-runtime/rocr-runtime-6.3.0.ebuild
similarity index 71%
rename from dev-libs/rocr-runtime/rocr-runtime-6.2.4.ebuild
rename to dev-libs/rocr-runtime/rocr-runtime-6.3.0.ebuild
index dfbf8f00ebddf..0fe1225bfb408 100644
--- a/dev-libs/rocr-runtime/rocr-runtime-6.2.4.ebuild
+++ b/dev-libs/rocr-runtime/rocr-runtime-6.3.0.ebuild
@@ -3,26 +3,22 @@
 
 EAPI=8
 
-LLVM_COMPAT=( 18 )
+LLVM_COMPAT=( 19 )
 
 inherit cmake flag-o-matic llvm-r1
 
 if [[ ${PV} == *9999 ]] ; then
 	EGIT_REPO_URI="https://github.com/ROCm/ROCR-Runtime/"
 	inherit git-r3
-	S="${WORKDIR}/${P}/src"
+	S="${WORKDIR}/${P}"
 else
 	SRC_URI="https://github.com/ROCm/ROCR-Runtime/archive/rocm-${PV}.tar.gz -> ${P}.tar.gz"
-	S="${WORKDIR}/ROCR-Runtime-rocm-${PV}/src"
+	S="${WORKDIR}/ROCR-Runtime-rocm-${PV}"
 	KEYWORDS="~amd64"
 fi
 
 DESCRIPTION="Radeon Open Compute Runtime"
 HOMEPAGE="https://github.com/ROCm/ROCR-Runtime"
-PATCHES=(
-	"${FILESDIR}/${PN}-4.3.0_no-aqlprofiler.patch"
-	"${FILESDIR}/${PN}-5.7.1-extend-isa-compatibility-check.patch"
-)
 
 LICENSE="MIT"
 SLOT="0/$(ver_cut 1-2)"
@@ -31,8 +27,8 @@ IUSE="debug"
 COMMON_DEPEND="dev-libs/elfutils
 	x11-libs/libdrm"
 DEPEND="${COMMON_DEPEND}
-	>=dev-libs/roct-thunk-interface-${PV}
-	>=dev-libs/rocm-device-libs-${PV}
+	dev-libs/roct-thunk-interface:${SLOT}
+	dev-libs/rocm-device-libs:${SLOT}
 	$(llvm_gen_dep '
 		llvm-core/clang:${LLVM_SLOT}=
 		llvm-core/lld:${LLVM_SLOT}=
@@ -42,10 +38,21 @@ RDEPEND="${DEPEND}"
 BDEPEND="app-editors/vim-core"
 	# vim-core is needed for "xxd"
 
+PATCHES=(
+	"${FILESDIR}/${PN}-6.3.0-use-system-hsakmt.patch"
+	"${FILESDIR}/${PN}-6.3.0-musl.patch"
+)
+
 src_prepare() {
+	cd "${S}/runtime/hsa-runtime" || die
+	eapply "${FILESDIR}/${PN}-4.3.0_no-aqlprofiler.patch"
+	eapply "${FILESDIR}/${PN}-5.7.1-extend-isa-compatibility-check.patch"
+	eapply "${FILESDIR}/${PN}-6.2.2-gcc15-stdint.patch"
+
 	# Gentoo installs "*.bc" to "/usr/lib" instead of a "[path]/bitcode" directory ...
 	sed -e "s:-O2:--rocm-path=${EPREFIX}/usr/lib/ -O2:" -i image/blit_src/CMakeLists.txt || die
 
+	cd "${S}" || die
 	cmake_src_prepare
 }
 
@@ -56,5 +63,6 @@ src_configure() {
 	filter-lto
 
 	use debug || append-cxxflags "-DNDEBUG"
+
 	cmake_src_configure
 }