diff --git a/sys-apps/locale-gen/locale-gen-3.2.ebuild b/sys-apps/locale-gen/locale-gen-3.2-r1.ebuild
similarity index 71%
rename from sys-apps/locale-gen/locale-gen-3.2.ebuild
rename to sys-apps/locale-gen/locale-gen-3.2-r1.ebuild
index 45a38c7dfc251..832a9c0ffdf13 100644
--- a/sys-apps/locale-gen/locale-gen-3.2.ebuild
+++ b/sys-apps/locale-gen/locale-gen-3.2-r1.ebuild
@@ -18,11 +18,25 @@ fi
 LICENSE="GPL-2"
 SLOT="0"
 
+# In-place editing became safer in v5.28.
+BDEPEND="
+	>=dev-lang/perl-5.28
+"
 RDEPEND="
 	>=dev-lang/perl-5.36
 	!<sys-libs/glibc-2.37-r3
 "
 
+src_prepare() {
+	# EPREFIX is readonly.
+	local -x MY_EPREFIX=${EPREFIX}
+
+	eapply_user
+
+	perl -pi -e '$f //= ($. == 1 && s/^#!\K\//$ENV{MY_EPREFIX}\//); END { exit !$f }' "${PN}" \
+	|| die "Failed to prefixify ${PN}"
+}
+
 src_install() {
 	dosbin locale-gen
 	doman *.[0-8]
diff --git a/sys-apps/locale-gen/locale-gen-3.3.ebuild b/sys-apps/locale-gen/locale-gen-3.3-r1.ebuild
similarity index 71%
rename from sys-apps/locale-gen/locale-gen-3.3.ebuild
rename to sys-apps/locale-gen/locale-gen-3.3-r1.ebuild
index 45a38c7dfc251..832a9c0ffdf13 100644
--- a/sys-apps/locale-gen/locale-gen-3.3.ebuild
+++ b/sys-apps/locale-gen/locale-gen-3.3-r1.ebuild
@@ -18,11 +18,25 @@ fi
 LICENSE="GPL-2"
 SLOT="0"
 
+# In-place editing became safer in v5.28.
+BDEPEND="
+	>=dev-lang/perl-5.28
+"
 RDEPEND="
 	>=dev-lang/perl-5.36
 	!<sys-libs/glibc-2.37-r3
 "
 
+src_prepare() {
+	# EPREFIX is readonly.
+	local -x MY_EPREFIX=${EPREFIX}
+
+	eapply_user
+
+	perl -pi -e '$f //= ($. == 1 && s/^#!\K\//$ENV{MY_EPREFIX}\//); END { exit !$f }' "${PN}" \
+	|| die "Failed to prefixify ${PN}"
+}
+
 src_install() {
 	dosbin locale-gen
 	doman *.[0-8]
diff --git a/sys-apps/locale-gen/locale-gen-9999.ebuild b/sys-apps/locale-gen/locale-gen-9999.ebuild
index b676a0c54f01a..b3bcb3b41b7ab 100644
--- a/sys-apps/locale-gen/locale-gen-9999.ebuild
+++ b/sys-apps/locale-gen/locale-gen-9999.ebuild
@@ -27,6 +27,16 @@ RDEPEND="
 	!<sys-libs/glibc-2.37-r3
 "
 
+src_prepare() {
+	# EPREFIX is readonly.
+	local -x MY_EPREFIX=${EPREFIX}
+
+	eapply_user
+
+	perl -pi -e '$f //= ($. == 1 && s/^#!\K\//$ENV{MY_EPREFIX}\//); END { exit !$f }' "${PN}" \
+	|| die "Failed to prefixify ${PN}"
+}
+
 src_install() {
 	dosbin locale-gen
 	doman *.[0-8]