diff --git a/app-arch/libdeflate/libdeflate-1.20.ebuild b/app-arch/libdeflate/libdeflate-1.20.ebuild
index 62ed3cb5e5928..395b2234ceea4 100644
--- a/app-arch/libdeflate/libdeflate-1.20.ebuild
+++ b/app-arch/libdeflate/libdeflate-1.20.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=8
 
-inherit cmake
+inherit cmake-multilib
 
 DESCRIPTION="Heavily optimized DEFLATE/zlib/gzip (de)compression"
 HOMEPAGE="https://github.com/ebiggers/libdeflate"
@@ -31,7 +31,7 @@ REQUIRED_USE="
 "
 
 DEPEND="
-	test? ( sys-libs/zlib )
+	test? ( sys-libs/zlib[${MULTILIB_USEDEP}] )
 "
 
 PATCHES=(
@@ -55,5 +55,5 @@ src_configure() {
 		-DLIBDEFLATE_BUILD_TESTS="$(usex test)"
 	)
 
-	cmake_src_configure
+	cmake-multilib_src_configure
 }
diff --git a/app-arch/libdeflate/libdeflate-9999.ebuild b/app-arch/libdeflate/libdeflate-9999.ebuild
index 2ed3a652def27..395b2234ceea4 100644
--- a/app-arch/libdeflate/libdeflate-9999.ebuild
+++ b/app-arch/libdeflate/libdeflate-9999.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=8
 
-inherit cmake
+inherit cmake-multilib
 
 DESCRIPTION="Heavily optimized DEFLATE/zlib/gzip (de)compression"
 HOMEPAGE="https://github.com/ebiggers/libdeflate"
@@ -13,7 +13,7 @@ if [[ ${PV} == *9999* ]]; then
 	EGIT_REPO_URI="https://github.com/ebiggers/libdeflate.git"
 else
 	SRC_URI="https://github.com/ebiggers/libdeflate/archive/v${PV}.tar.gz -> ${P}.tar.gz"
-	KEYWORDS="~amd64 ~x86"
+	KEYWORDS="~alpha ~amd64 ~arm ~arm64 ~hppa ~ia64 ~loong ~ppc ~ppc64 ~riscv ~s390 ~sparc ~x86"
 fi
 
 LICENSE="MIT"
@@ -31,7 +31,7 @@ REQUIRED_USE="
 "
 
 DEPEND="
-	test? ( sys-libs/zlib )
+	test? ( sys-libs/zlib[${MULTILIB_USEDEP}] )
 "
 
 PATCHES=(
@@ -55,5 +55,5 @@ src_configure() {
 		-DLIBDEFLATE_BUILD_TESTS="$(usex test)"
 	)
 
-	cmake_src_configure
+	cmake-multilib_src_configure
 }