diff --git a/app-portage/gpyutils/files/implementations.txt b/app-portage/gpyutils/files/implementations.txt
index 45705e04e3e11..95b321ec9437a 100644
--- a/app-portage/gpyutils/files/implementations.txt
+++ b/app-portage/gpyutils/files/implementations.txt
@@ -23,6 +23,7 @@ python3_10		old	3.10
 python3_11		old	3.11
 python3_12		current	3.12
 python3_13		experimental	3.13
+python3_13t		experimental	3.13t
 
 pypy1_8	2.7-pypy-1.8	dead	p1.8
 pypy1_9	2.7-pypy-1.9	dead	p1.9
diff --git a/dev-lang/python/python-3.13.0-r100.ebuild b/dev-lang/python/python-3.13.0-r100.ebuild
index 6c78c5cb367b0..42c893fb4e747 100644
--- a/dev-lang/python/python-3.13.0-r100.ebuild
+++ b/dev-lang/python/python-3.13.0-r100.ebuild
@@ -368,6 +368,7 @@ src_configure() {
 
 			# Fails in profiling run, passes in src_test().
 			-x test_capi
+			-x test_external_inspection
 		)
 
 		# Arch-specific skips.  See #931888 for a collection of these.
diff --git a/dev-python/appdirs/appdirs-1.4.4-r3.ebuild b/dev-python/appdirs/appdirs-1.4.4-r3.ebuild
index a76ea1dae722a..3ba4839c4dc46 100644
--- a/dev-python/appdirs/appdirs-1.4.4-r3.ebuild
+++ b/dev-python/appdirs/appdirs-1.4.4-r3.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1
 
diff --git a/dev-python/build/build-1.2.2_p1.ebuild b/dev-python/build/build-1.2.2_p1.ebuild
index b99b7494fb84a..183bde40addce 100644
--- a/dev-python/build/build-1.2.2_p1.ebuild
+++ b/dev-python/build/build-1.2.2_p1.ebuild
@@ -5,7 +5,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=flit
 PYTHON_TESTED=( python3_{10..13} pypy3 )
-PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" )
+PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" python3_13t )
 
 inherit distutils-r1
 
diff --git a/dev-python/editables/editables-0.5.ebuild b/dev-python/editables/editables-0.5.ebuild
index f80dba5505240..413208f02b6cc 100644
--- a/dev-python/editables/editables-0.5.ebuild
+++ b/dev-python/editables/editables-0.5.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( pypy3 python3_{10..13} )
+PYTHON_COMPAT=( pypy3 python3_{10..13} python3_13t )
 
 inherit distutils-r1
 
diff --git a/dev-python/flit-core/flit-core-3.9.0.ebuild b/dev-python/flit-core/flit-core-3.9.0.ebuild
index 5df54ae00ab2a..bbd23d9c0e2c4 100644
--- a/dev-python/flit-core/flit-core-3.9.0.ebuild
+++ b/dev-python/flit-core/flit-core-3.9.0.ebuild
@@ -5,7 +5,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=standalone
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/freezegun/freezegun-1.5.1.ebuild b/dev-python/freezegun/freezegun-1.5.1.ebuild
index 351cd57c6a9a0..e73658f3fb4ae 100644
--- a/dev-python/freezegun/freezegun-1.5.1.ebuild
+++ b/dev-python/freezegun/freezegun-1.5.1.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
@@ -32,7 +32,7 @@ distutils_enable_tests pytest
 python_test() {
 	local EPYTEST_DESELECT=()
 	case ${EPYTHON} in
-		python3.13)
+		python3.13*)
 			EPYTEST_DESELECT+=(
 				# https://github.com/spulec/freezegun/issues/547
 				tests/test_datetimes.py::TestUnitTestMethodDecorator::test_method_decorator_works_on_unittest_kwarg_frozen_time
diff --git a/dev-python/gpep517/gpep517-16.ebuild b/dev-python/gpep517/gpep517-16.ebuild
index 0bf96edc1ec7c..9ce81ecad415f 100644
--- a/dev-python/gpep517/gpep517-16.ebuild
+++ b/dev-python/gpep517/gpep517-16.ebuild
@@ -5,7 +5,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=no
-PYTHON_COMPAT=( pypy3 python3_{10..13} )
+PYTHON_COMPAT=( pypy3 python3_{10..13} python3_13t )
 
 inherit distutils-r1
 
diff --git a/dev-python/hatch-vcs/hatch-vcs-0.4.0.ebuild b/dev-python/hatch-vcs/hatch-vcs-0.4.0.ebuild
index a814774845fe8..3e52b2c3cc2fb 100644
--- a/dev-python/hatch-vcs/hatch-vcs-0.4.0.ebuild
+++ b/dev-python/hatch-vcs/hatch-vcs-0.4.0.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=hatchling
-PYTHON_COMPAT=( pypy3 python3_{10..13} )
+PYTHON_COMPAT=( pypy3 python3_{10..13} python3_13t )
 
 inherit distutils-r1
 
diff --git a/dev-python/hatchling/hatchling-1.25.0.ebuild b/dev-python/hatchling/hatchling-1.25.0.ebuild
index e5d3d13324b3b..731a9a1edeab3 100644
--- a/dev-python/hatchling/hatchling-1.25.0.ebuild
+++ b/dev-python/hatchling/hatchling-1.25.0.ebuild
@@ -5,7 +5,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=standalone
 PYTHON_TESTED=( pypy3 python3_{10..13} )
-PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" )
+PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" python3_13t )
 
 inherit distutils-r1
 
diff --git a/dev-python/iniconfig/iniconfig-2.0.0.ebuild b/dev-python/iniconfig/iniconfig-2.0.0.ebuild
index 3a89f831343a0..8cd35efb25c15 100644
--- a/dev-python/iniconfig/iniconfig-2.0.0.ebuild
+++ b/dev-python/iniconfig/iniconfig-2.0.0.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=hatchling
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1
 
diff --git a/dev-python/installer/installer-0.7.0.ebuild b/dev-python/installer/installer-0.7.0.ebuild
index bf6f7a465683a..e421f44f34fd7 100644
--- a/dev-python/installer/installer-0.7.0.ebuild
+++ b/dev-python/installer/installer-0.7.0.ebuild
@@ -5,7 +5,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=no
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/jaraco-classes/jaraco-classes-3.4.0.ebuild b/dev-python/jaraco-classes/jaraco-classes-3.4.0.ebuild
index b21bd4343f26b..f8ef7413b7011 100644
--- a/dev-python/jaraco-classes/jaraco-classes-3.4.0.ebuild
+++ b/dev-python/jaraco-classes/jaraco-classes-3.4.0.ebuild
@@ -6,7 +6,7 @@ EAPI=8
 DISTUTILS_USE_PEP517=setuptools
 PYPI_NO_NORMALIZE=1
 PYPI_PN=${PN/-/.}
-PYTHON_COMPAT=( pypy3 python3_{10..13} )
+PYTHON_COMPAT=( pypy3 python3_{10..13} python3_13t )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/jaraco-context/jaraco-context-6.0.1.ebuild b/dev-python/jaraco-context/jaraco-context-6.0.1.ebuild
index 751b9a71279ac..82f7990ca69b7 100644
--- a/dev-python/jaraco-context/jaraco-context-6.0.1.ebuild
+++ b/dev-python/jaraco-context/jaraco-context-6.0.1.ebuild
@@ -6,7 +6,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=flit
 PYPI_PN=${PN/-/.}
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/jaraco-functools/jaraco-functools-4.1.0.ebuild b/dev-python/jaraco-functools/jaraco-functools-4.1.0.ebuild
index e4e184ad98045..a349740b25d0b 100644
--- a/dev-python/jaraco-functools/jaraco-functools-4.1.0.ebuild
+++ b/dev-python/jaraco-functools/jaraco-functools-4.1.0.ebuild
@@ -6,7 +6,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=flit
 PYPI_PN=${PN/-/.}
-PYTHON_COMPAT=( pypy3 python3_{10..13} )
+PYTHON_COMPAT=( pypy3 python3_{10..13} python3_13t )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/jaraco-text/jaraco-text-4.0.0.ebuild b/dev-python/jaraco-text/jaraco-text-4.0.0.ebuild
index b160fc4e1fb9e..b0f4cc114ff56 100644
--- a/dev-python/jaraco-text/jaraco-text-4.0.0.ebuild
+++ b/dev-python/jaraco-text/jaraco-text-4.0.0.ebuild
@@ -6,7 +6,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=flit
 PYPI_PN=${PN/-/.}
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/more-itertools/more-itertools-10.5.0.ebuild b/dev-python/more-itertools/more-itertools-10.5.0.ebuild
index b45d5bbe71c5f..f7ed9cbc11cb7 100644
--- a/dev-python/more-itertools/more-itertools-10.5.0.ebuild
+++ b/dev-python/more-itertools/more-itertools-10.5.0.ebuild
@@ -5,7 +5,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=flit
 PYPI_NO_NORMALIZE=1
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/packaging/packaging-24.1.ebuild b/dev-python/packaging/packaging-24.1.ebuild
index 2fad66ebf2ef9..1f3e1b6b1bfd9 100644
--- a/dev-python/packaging/packaging-24.1.ebuild
+++ b/dev-python/packaging/packaging-24.1.ebuild
@@ -5,7 +5,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/pathspec/pathspec-0.12.1.ebuild b/dev-python/pathspec/pathspec-0.12.1.ebuild
index b14ddd482bdf7..52c35a10189d1 100644
--- a/dev-python/pathspec/pathspec-0.12.1.ebuild
+++ b/dev-python/pathspec/pathspec-0.12.1.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/pexpect/files/pexpect-4.9.0-py313.patch b/dev-python/pexpect/files/pexpect-4.9.0-py313.patch
new file mode 100644
index 0000000000000..838cfdd22d86c
--- /dev/null
+++ b/dev-python/pexpect/files/pexpect-4.9.0-py313.patch
@@ -0,0 +1,37 @@
+From 95d09c54d2502d8d48f2da591089ceb6d09df056 Mon Sep 17 00:00:00 2001
+From: =?UTF-8?q?Miro=20Hron=C4=8Dok?= <miro@hroncok.cz>
+Date: Wed, 29 May 2024 12:21:52 +0200
+Subject: [PATCH] Force NO_COLOR=1 to fix test failures with Python 3.13+ REPL
+
+Python 3.13+ has colors now. Always setting this variable should be safe.
+---
+ pexpect/replwrap.py    | 2 +-
+ tests/test_replwrap.py | 2 +-
+ 2 files changed, 2 insertions(+), 2 deletions(-)
+
+diff --git a/pexpect/replwrap.py b/pexpect/replwrap.py
+index 08dbd5e8..c8714a23 100644
+--- a/pexpect/replwrap.py
++++ b/pexpect/replwrap.py
+@@ -35,7 +35,7 @@ def __init__(self, cmd_or_spawn, orig_prompt, prompt_change,
+                  continuation_prompt=PEXPECT_CONTINUATION_PROMPT,
+                  extra_init_cmd=None):
+         if isinstance(cmd_or_spawn, basestring):
+-            self.child = pexpect.spawn(cmd_or_spawn, echo=False, encoding='utf-8')
++            self.child = pexpect.spawn(cmd_or_spawn, echo=False, encoding='utf-8', env={'NO_COLOR': '1'})
+         else:
+             self.child = cmd_or_spawn
+         if self.child.echo:
+diff --git a/tests/test_replwrap.py b/tests/test_replwrap.py
+index ddafa5d6..5ac782a4 100644
+--- a/tests/test_replwrap.py
++++ b/tests/test_replwrap.py
+@@ -124,7 +124,7 @@ def test_no_change_prompt(self):
+         if platform.python_implementation() == 'PyPy':
+             raise unittest.SkipTest(skip_pypy)
+ 
+-        child = pexpect.spawn(sys.executable, echo=False, timeout=5, encoding='utf-8')
++        child = pexpect.spawn(sys.executable, echo=False, timeout=5, encoding='utf-8', env={'NO_COLOR': '1'})
+         # prompt_change=None should mean no prompt change
+         py = replwrap.REPLWrapper(child, u">>> ", prompt_change=None,
+                                   continuation_prompt=u"... ")
diff --git a/dev-python/pexpect/pexpect-4.9.0.ebuild b/dev-python/pexpect/pexpect-4.9.0.ebuild
index 93f20c1b16ab0..a6a72d9e35dc9 100644
--- a/dev-python/pexpect/pexpect-4.9.0.ebuild
+++ b/dev-python/pexpect/pexpect-4.9.0.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 PYTHON_REQ_USE="threads(+)"
 
 inherit distutils-r1 pypi
@@ -29,6 +29,11 @@ distutils_enable_tests pytest
 distutils_enable_sphinx doc \
 	dev-python/sphinxcontrib-github-alt
 
+PATCHES=(
+	# https://github.com/pexpect/pexpect/pull/794
+	"${FILESDIR}/${P}-py313.patch"
+)
+
 src_test() {
 	# workaround new readline defaults
 	echo "set enable-bracketed-paste off" > "${T}"/inputrc || die
@@ -47,16 +52,6 @@ python_test() {
 		tests/test_env.py::TestCaseEnv::test_spawn_uses_env
 	)
 
-	case ${EPYTHON} in
-		python3.13)
-			EPYTEST_DESELECT+=(
-				# TODO: changes in python3.13's prompt?
-				tests/test_replwrap.py::REPLWrapTestCase::test_python
-				tests/test_replwrap.py::REPLWrapTestCase::test_no_change_prompt
-			)
-			;;
-	esac
-
 	local -x PYTEST_DISABLE_PLUGIN_AUTOLOAD=1
 	epytest
 }
diff --git a/dev-python/platformdirs/platformdirs-4.3.6.ebuild b/dev-python/platformdirs/platformdirs-4.3.6.ebuild
index a67ec460cbe7a..d1f6244a070ec 100644
--- a/dev-python/platformdirs/platformdirs-4.3.6.ebuild
+++ b/dev-python/platformdirs/platformdirs-4.3.6.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/pluggy/pluggy-1.5.0.ebuild b/dev-python/pluggy/pluggy-1.5.0.ebuild
index fd1a0a67e5a44..f9e611044092c 100644
--- a/dev-python/pluggy/pluggy-1.5.0.ebuild
+++ b/dev-python/pluggy/pluggy-1.5.0.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/portend/portend-3.2.0.ebuild b/dev-python/portend/portend-3.2.0.ebuild
index 7f55187e17bec..3a98b2d469644 100644
--- a/dev-python/portend/portend-3.2.0.ebuild
+++ b/dev-python/portend/portend-3.2.0.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/pretend/pretend-1.0.9-r2.ebuild b/dev-python/pretend/pretend-1.0.9-r2.ebuild
index ee9ec29d01501..9359feb683d7f 100644
--- a/dev-python/pretend/pretend-1.0.9-r2.ebuild
+++ b/dev-python/pretend/pretend-1.0.9-r2.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1
 
diff --git a/dev-python/ptyprocess/ptyprocess-0.7.0-r1.ebuild b/dev-python/ptyprocess/ptyprocess-0.7.0-r1.ebuild
index cd49d3d541aea..32121931e6d33 100644
--- a/dev-python/ptyprocess/ptyprocess-0.7.0-r1.ebuild
+++ b/dev-python/ptyprocess/ptyprocess-0.7.0-r1.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/pyproject-hooks/pyproject-hooks-1.2.0.ebuild b/dev-python/pyproject-hooks/pyproject-hooks-1.2.0.ebuild
index 3853b5b222816..98e5a886f00e9 100644
--- a/dev-python/pyproject-hooks/pyproject-hooks-1.2.0.ebuild
+++ b/dev-python/pyproject-hooks/pyproject-hooks-1.2.0.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/pytest-freezer/pytest-freezer-0.4.8.ebuild b/dev-python/pytest-freezer/pytest-freezer-0.4.8.ebuild
index a3fb50286042c..f347fbb4c4dae 100644
--- a/dev-python/pytest-freezer/pytest-freezer-0.4.8.ebuild
+++ b/dev-python/pytest-freezer/pytest-freezer-0.4.8.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( pypy3 python3_{10..13} )
+PYTHON_COMPAT=( pypy3 python3_{10..13} python3_13t )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/pytest-mock/pytest-mock-3.14.0.ebuild b/dev-python/pytest-mock/pytest-mock-3.14.0.ebuild
index 8aebb3a323d87..9108b4a8bdd35 100644
--- a/dev-python/pytest-mock/pytest-mock-3.14.0.ebuild
+++ b/dev-python/pytest-mock/pytest-mock-3.14.0.ebuild
@@ -6,7 +6,7 @@ EAPI=8
 DISTUTILS_USE_PEP517=setuptools
 PYPI_NO_NORMALIZE=1
 PYTHON_TESTED=( python3_{10..13} pypy3 )
-PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" )
+PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" python3_13t )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/pytest/pytest-8.3.3.ebuild b/dev-python/pytest/pytest-8.3.3.ebuild
index 408c5622c9f84..33f394085d54b 100644
--- a/dev-python/pytest/pytest-8.3.3.ebuild
+++ b/dev-python/pytest/pytest-8.3.3.ebuild
@@ -5,7 +5,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
 PYTHON_TESTED=( python3_{10..13} pypy3 )
-PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" )
+PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" python3_13t )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/python-dateutil/python-dateutil-2.9.0_p0.ebuild b/dev-python/python-dateutil/python-dateutil-2.9.0_p0.ebuild
index 6b3ced20bfc3e..74059ed6728cd 100644
--- a/dev-python/python-dateutil/python-dateutil-2.9.0_p0.ebuild
+++ b/dev-python/python-dateutil/python-dateutil-2.9.0_p0.ebuild
@@ -5,7 +5,8 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
 PYPI_NO_NORMALIZE=1
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_FULLY_TESTED=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( "${PYTHON_FULLY_TESTED[@]}" python3_13t )
 
 inherit distutils-r1 pypi
 
@@ -28,7 +29,9 @@ BDEPEND="
 	dev-python/setuptools-scm[${PYTHON_USEDEP}]
 	test? (
 		dev-python/freezegun[${PYTHON_USEDEP}]
-		dev-python/hypothesis[${PYTHON_USEDEP}]
+		$(python_gen_cond_dep '
+			dev-python/hypothesis[${PYTHON_USEDEP}]
+		' "${PYTHON_FULLY_TESTED[@]}")
 	)
 "
 
@@ -45,3 +48,15 @@ python_prepare_all() {
 
 	distutils-r1_python_prepare_all
 }
+
+python_test() {
+	local EPYTEST_IGNORE=()
+	if ! has_version "dev-python/hypothesis[${PYTHON_USEDEP}]"; then
+		EPYTEST_IGNORE+=(
+			tests/property
+		)
+	fi
+
+	local -x PYTEST_DISABLE_PLUGIN_AUTOLOAD=1
+	epytest
+}
diff --git a/dev-python/setuptools-scm/metadata.xml b/dev-python/setuptools-scm/metadata.xml
index c5b76d75363f6..c42621375597f 100644
--- a/dev-python/setuptools-scm/metadata.xml
+++ b/dev-python/setuptools-scm/metadata.xml
@@ -8,6 +8,6 @@
 	<stabilize-allarches/>
 	<upstream>
 		<remote-id type="pypi">setuptools-scm</remote-id>
-		<remote-id type="github">pypa/setuptools_scm</remote-id>
+		<remote-id type="github">pypa/setuptools-scm</remote-id>
 	</upstream>
 </pkgmetadata>
diff --git a/dev-python/setuptools-scm/setuptools-scm-8.1.0.ebuild b/dev-python/setuptools-scm/setuptools-scm-8.1.0.ebuild
index 57a099a021e76..21492431d57d4 100644
--- a/dev-python/setuptools-scm/setuptools-scm-8.1.0.ebuild
+++ b/dev-python/setuptools-scm/setuptools-scm-8.1.0.ebuild
@@ -5,13 +5,13 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=standalone
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
 DESCRIPTION="Manage versions by scm tags via setuptools"
 HOMEPAGE="
-	https://github.com/pypa/setuptools_scm/
+	https://github.com/pypa/setuptools-scm/
 	https://pypi.org/project/setuptools-scm/
 "
 
diff --git a/dev-python/setuptools/setuptools-74.1.3.ebuild b/dev-python/setuptools/setuptools-74.1.3.ebuild
index 83bdd551d3159..652157bb1a0ed 100644
--- a/dev-python/setuptools/setuptools-74.1.3.ebuild
+++ b/dev-python/setuptools/setuptools-74.1.3.ebuild
@@ -8,7 +8,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=standalone
 PYTHON_TESTED=( python3_{10..13} pypy3 )
-PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" )
+PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" python3_13t )
 PYTHON_REQ_USE="xml(+)"
 
 inherit distutils-r1 pypi
diff --git a/dev-python/setuptools/setuptools-75.1.0.ebuild b/dev-python/setuptools/setuptools-75.1.0.ebuild
index df219ec843475..e04c2c70c4cd2 100644
--- a/dev-python/setuptools/setuptools-75.1.0.ebuild
+++ b/dev-python/setuptools/setuptools-75.1.0.ebuild
@@ -8,7 +8,7 @@ EAPI=8
 
 DISTUTILS_USE_PEP517=standalone
 PYTHON_TESTED=( python3_{10..13} pypy3 )
-PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" )
+PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" python3_13t )
 PYTHON_REQ_USE="xml(+)"
 
 inherit distutils-r1 pypi
diff --git a/dev-python/six/six-1.16.0-r1.ebuild b/dev-python/six/six-1.16.0-r1.ebuild
index 4554e1d0fd4a8..d7f93534815aa 100644
--- a/dev-python/six/six-1.16.0-r1.ebuild
+++ b/dev-python/six/six-1.16.0-r1.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
@@ -22,14 +22,14 @@ distutils_enable_sphinx documentation --no-autodoc
 distutils_enable_tests pytest
 
 python_test() {
-	local EPYTEST_DESELECT=()
+	local EPYTEST_DESELECT=(
+		# requires USE=gdb on CPython, no point in forcing the dep
+		# also missing on PyPy
+		'test_six.py::test_move_items[dbm_ndbm]'
+	)
+
 	case ${EPYTHON} in
-		pypy3)
-			EPYTEST_DESELECT+=(
-				'test_six.py::test_move_items[dbm_ndbm]'
-			)
-			;;
-		python3.13)
+		python3.13*)
 			EPYTEST_DESELECT+=(
 				'test_six.py::test_move_items[tkinter_tix]'
 			)
diff --git a/dev-python/tempora/tempora-5.7.0.ebuild b/dev-python/tempora/tempora-5.7.0.ebuild
index 10b1913f46c10..7b8fa416b2ac5 100644
--- a/dev-python/tempora/tempora-5.7.0.ebuild
+++ b/dev-python/tempora/tempora-5.7.0.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=setuptools
-PYTHON_TESTED=( pypy3 python3_{10..13} )
+PYTHON_TESTED=( pypy3 python3_{10..13} python3_13t )
 PYTHON_COMPAT=( "${PYTHON_TESTED[@]}" )
 
 inherit distutils-r1 pypi
diff --git a/dev-python/testpath/testpath-0.6.0.ebuild b/dev-python/testpath/testpath-0.6.0.ebuild
index f1f17b0dcdd3d..b53c282bb015a 100644
--- a/dev-python/testpath/testpath-0.6.0.ebuild
+++ b/dev-python/testpath/testpath-0.6.0.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( pypy3 python3_{10..13} )
+PYTHON_COMPAT=( pypy3 python3_{10..13} python3_13t )
 
 inherit distutils-r1
 
diff --git a/dev-python/trove-classifiers/trove-classifiers-2024.10.13.ebuild b/dev-python/trove-classifiers/trove-classifiers-2024.10.13.ebuild
index 0fb0bac459d45..b19f32b12f716 100644
--- a/dev-python/trove-classifiers/trove-classifiers-2024.10.13.ebuild
+++ b/dev-python/trove-classifiers/trove-classifiers-2024.10.13.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( pypy3 python3_{10..13} )
+PYTHON_COMPAT=( pypy3 python3_{10..13} python3_13t )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/typing-extensions/typing-extensions-4.12.2.ebuild b/dev-python/typing-extensions/typing-extensions-4.12.2.ebuild
index 56e5a8efce66e..483ce343ed9a6 100644
--- a/dev-python/typing-extensions/typing-extensions-4.12.2.ebuild
+++ b/dev-python/typing-extensions/typing-extensions-4.12.2.ebuild
@@ -4,7 +4,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
diff --git a/dev-python/wheel/files/wheel-0.44.0-ft.patch b/dev-python/wheel/files/wheel-0.44.0-ft.patch
new file mode 100644
index 0000000000000..600318dc275ef
--- /dev/null
+++ b/dev-python/wheel/files/wheel-0.44.0-ft.patch
@@ -0,0 +1,38 @@
+From d30f834fcec7ecdbb74e263789db2fbe9ff37e99 Mon Sep 17 00:00:00 2001
+From: =?UTF-8?q?Micha=C5=82=20G=C3=B3rny?= <mgorny@gentoo.org>
+Date: Fri, 11 Oct 2024 16:12:50 +0200
+Subject: [PATCH] Skip abi3 tests when freethreading Python build is used
+
+Skip the tests using abi3 extension when the freethreading build is
+used, as Python 3.13 freethreading does not support the limited API
+and its use results in a build error.
+
+Fixes #636
+---
+ tests/conftest.py | 3 ++-
+ 1 file changed, 2 insertions(+), 1 deletion(-)
+
+diff --git a/tests/conftest.py b/tests/conftest.py
+index 5ee84da..d5bd356 100644
+--- a/tests/conftest.py
++++ b/tests/conftest.py
+@@ -7,6 +7,7 @@ from __future__ import annotations
+ import os.path
+ import subprocess
+ import sys
++import sysconfig
+ 
+ import pytest
+ 
+@@ -22,7 +23,7 @@ def wheels_and_eggs(tmp_path_factory):
+         "unicode.dist",
+     )
+ 
+-    if sys.platform != "win32":
++    if sys.platform != "win32" and sysconfig.get_config_var("Py_GIL_DISABLED") != 1:
+         # ABI3 extensions don't really work on Windows
+         test_distributions += ("abi3extension.dist",)
+ 
+-- 
+2.47.0
+
diff --git a/dev-python/wheel/wheel-0.44.0.ebuild b/dev-python/wheel/wheel-0.44.0.ebuild
index effd34bd7d1a8..aa0df30e0b2cc 100644
--- a/dev-python/wheel/wheel-0.44.0.ebuild
+++ b/dev-python/wheel/wheel-0.44.0.ebuild
@@ -5,7 +5,7 @@
 EAPI=8
 
 DISTUTILS_USE_PEP517=flit
-PYTHON_COMPAT=( python3_{10..13} pypy3 )
+PYTHON_COMPAT=( python3_{10..13} python3_13t pypy3 )
 
 inherit distutils-r1 pypi
 
@@ -36,10 +36,20 @@ EPYTEST_DESELECT=(
 distutils_enable_tests pytest
 
 src_prepare() {
+	local PATCHES=(
+		# https://github.com/pypa/wheel/pull/637
+		"${FILESDIR}/${P}-ft.patch"
+	)
+
+	distutils-r1_src_prepare
+
 	# unbundle packaging
 	rm -r src/wheel/vendored || die
 	sed -i -e 's:\.vendored\.::' src/wheel/*.py || die
 	sed -i -e 's:wheel\.vendored\.::' tests/*.py || die
-
-	distutils-r1_src_prepare
+}
+
+python_test() {
+	local -x PYTEST_DISABLE_PLUGIN_AUTOLOAD=1
+	epytest
 }
diff --git a/eclass/distutils-r1.eclass b/eclass/distutils-r1.eclass
index c3a7d112b03f9..7ab8dcae3265a 100644
--- a/eclass/distutils-r1.eclass
+++ b/eclass/distutils-r1.eclass
@@ -1494,9 +1494,16 @@ distutils-r1_python_compile() {
 				# that this relies on the assumption that we're building
 				# from the oldest to the newest implementation,
 				# and the wheels are forward-compatible.
-				if [[ ( ! ${DISTUTILS_EXT} && ${whl} == *py3-none-any* ) ||
-					( ${EPYTHON} == python* && ${whl} == *-abi3-* ) ]]
-				then
+				if [[
+					( ! ${DISTUTILS_EXT} && ${whl} == *py3-none-any* ) ||
+					(
+						${EPYTHON} == python* &&
+						# freethreading does not support stable ABI
+						# at the moment
+						${EPYTHON} != *t &&
+						${whl} == *-abi3-*
+					)
+				]]; then
 					distutils_wheel_install "${BUILD_DIR}/install" "${whl}"
 					return
 				fi
diff --git a/eclass/python-r1.eclass b/eclass/python-r1.eclass
index 18f4dadfdd378..9b03a269e88b1 100644
--- a/eclass/python-r1.eclass
+++ b/eclass/python-r1.eclass
@@ -129,10 +129,6 @@ inherit multibuild python-utils-r1
 # depend on another Python package being built for the same Python
 # implementations.
 #
-# The generate USE-flag list is compatible with packages using python-r1
-# and python-distutils-ng eclasses. It must not be used on packages
-# using python.eclass.
-#
 # Example use:
 # @CODE
 # RDEPEND="dev-python/foo[${PYTHON_USEDEP}]"
diff --git a/eclass/python-utils-r1.eclass b/eclass/python-utils-r1.eclass
index 796be7ab456a5..555b6c561a18e 100644
--- a/eclass/python-utils-r1.eclass
+++ b/eclass/python-utils-r1.eclass
@@ -41,6 +41,7 @@ inherit multiprocessing toolchain-funcs
 _PYTHON_ALL_IMPLS=(
 	pypy3
 	python3_{10..13}
+	python3_13t
 )
 readonly _PYTHON_ALL_IMPLS
 
@@ -136,7 +137,7 @@ _python_set_impls() {
 			# please keep them in sync with _PYTHON_ALL_IMPLS
 			# and _PYTHON_HISTORICAL_IMPLS
 			case ${i} in
-				pypy3|python3_9|python3_1[0-3])
+				pypy3|python3_9|python3_1[0-3]|python3_13t)
 					;;
 				jython2_7|pypy|pypy1_[89]|pypy2_0|python2_[5-7]|python3_[1-9])
 					obsolete+=( "${i}" )
@@ -232,7 +233,7 @@ _python_impl_matches() {
 					return 0
 				;;
 			3.8|3.9|3.1[1-3])
-				[[ ${impl} == python${pattern/./_} ]] && return 0
+				[[ ${impl%t} == python${pattern/./_} ]] && return 0
 				;;
 			*)
 				# unify value style to allow lax matching
@@ -435,7 +436,7 @@ _python_export() {
 									or "")
 							EOF
 						)
-						val=${PYTHON}${flags}-config
+						val=${PYTHON%t}${flags}-config
 						;;
 					*)
 						die "${impl}: obtaining ${var} not supported"
diff --git a/eclass/tests/python-utils-r1.sh b/eclass/tests/python-utils-r1.sh
index 93cea324a3df0..732f53381b22b 100755
--- a/eclass/tests/python-utils-r1.sh
+++ b/eclass/tests/python-utils-r1.sh
@@ -64,7 +64,7 @@ tmpfile=$(mktemp)
 
 inherit python-utils-r1
 
-for minor in {10..13}; do
+for minor in {10..13} 13t; do
 	ebegin "Testing python3.${minor}"
 	eindent
 	test_var EPYTHON "python3_${minor}" "python3.${minor}"
@@ -72,9 +72,9 @@ for minor in {10..13}; do
 	if [[ -x /usr/bin/python3.${minor} ]]; then
 		abiflags=$(/usr/bin/python3.${minor} -c 'import sysconfig; print(sysconfig.get_config_var("ABIFLAGS"))')
 		test_var PYTHON_SITEDIR "python3_${minor}" "/usr/lib*/python3.${minor}/site-packages"
-		test_var PYTHON_INCLUDEDIR "python3_${minor}" "/usr/include/python3.${minor}${abiflags}"
-		test_var PYTHON_LIBPATH "python3_${minor}" "/usr/lib*/libpython3.${minor}${abiflags}$(get_libname)"
-		test_var PYTHON_CONFIG "python3_${minor}" "/usr/bin/python3.${minor}${abiflags}-config"
+		test_var PYTHON_INCLUDEDIR "python3_${minor}" "/usr/include/python3.${minor%t}${abiflags}"
+		test_var PYTHON_LIBPATH "python3_${minor}" "/usr/lib*/libpython3.${minor%t}${abiflags}$(get_libname)"
+		test_var PYTHON_CONFIG "python3_${minor}" "/usr/bin/python3.${minor%t}${abiflags}-config"
 		test_var PYTHON_CFLAGS "python3_${minor}" "*-I/usr/include/python3.${minor}*"
 		test_var PYTHON_LIBS "python3_${minor}" "*-lpython3.${minor}*"
 	fi
@@ -105,13 +105,13 @@ for minor in {10..13}; do
 	tend ${?}
 
 	# these tests apply to py3.8+ only
-	if [[ ${minor} -ge 8 ]]; then
+	if [[ ${minor%t} -ge 8 ]]; then
 		tbegin "Testing that _python_verify_patterns accepts stdlib version"
-		( _python_verify_patterns "3.${minor}" )
+		( _python_verify_patterns "3.${minor%t}" )
 		tend ${?}
 
 		tbegin "Testing _python_impl_matches on stdlib version"
-		_python_impl_matches "python3_${minor}" "3.${minor}"
+		_python_impl_matches "python3_${minor}" "3.${minor%t}"
 		tend ${?}
 	fi
 
diff --git a/metadata/install-qa-check.d/60python-site b/metadata/install-qa-check.d/60python-site
index facfb54f1b3cd..1a4ee0ca9f4e8 100644
--- a/metadata/install-qa-check.d/60python-site
+++ b/metadata/install-qa-check.d/60python-site
@@ -53,7 +53,7 @@ python_site_check() {
 
 		# check for packages installing outside site-packages
 		case ${CATEGORY}/${PN} in
-			dev-lang/python|dev-python/pypy*|dev-python/python-tests)
+			dev-lang/python|dev-lang/python-freethreading|dev-python/pypy*|dev-python/python-tests)
 				;;
 			*)
 				while IFS= read -d $'\0' -r f; do
diff --git a/profiles/base/package.use.force b/profiles/base/package.use.force
index 9d51b4e497030..800efe47743ba 100644
--- a/profiles/base/package.use.force
+++ b/profiles/base/package.use.force
@@ -253,6 +253,7 @@ dev-lang/python-exec python_targets_python3_10
 dev-lang/python-exec python_targets_python3_11
 dev-lang/python-exec python_targets_python3_12
 dev-lang/python-exec python_targets_python3_13
+dev-lang/python-exec python_targets_python3_13t
 dev-lang/python-exec python_targets_pypy3
 
 # Zac Medico <zmedico@gentoo.org> (2010-10-20)
diff --git a/profiles/base/use.stable.mask b/profiles/base/use.stable.mask
index 9167592b9e10a..d1197864f26b0 100644
--- a/profiles/base/use.stable.mask
+++ b/profiles/base/use.stable.mask
@@ -16,6 +16,8 @@ llvm_slot_19
 # Python implementations without stable keywords.
 python_targets_python3_13
 python_single_target_python3_13
+python_targets_python3_13t
+python_single_target_python3_13t
 python_targets_pypy3
 python_single_target_pypy3
 
diff --git a/profiles/desc/python_single_target.desc b/profiles/desc/python_single_target.desc
index 427e206dd196e..d168b301a8d8a 100644
--- a/profiles/desc/python_single_target.desc
+++ b/profiles/desc/python_single_target.desc
@@ -7,4 +7,5 @@ python3_10 - Build for Python 3.10 only
 python3_11 - Build for Python 3.11 only
 python3_12 - Build for Python 3.12 only
 python3_13 - Build for Python 3.13 only
+python3_13t - Build for Python 3.13 freethreading only
 pypy3 - Build for PyPy3 only
diff --git a/profiles/desc/python_targets.desc b/profiles/desc/python_targets.desc
index b48cc57e99fb9..298b54067be7f 100644
--- a/profiles/desc/python_targets.desc
+++ b/profiles/desc/python_targets.desc
@@ -7,4 +7,5 @@ python3_10 - Build with Python 3.10
 python3_11 - Build with Python 3.11
 python3_12 - Build with Python 3.12
 python3_13 - Build with Python 3.13
+python3_13t - Build with Python 3.13 freethreading
 pypy3 - Build with PyPy3
diff --git a/sci-mathematics/flint/files/flint-3.1.3_p1-fix-pc-location.patch b/sci-mathematics/flint/files/flint-3.1.3_p1-fix-pc-location.patch
new file mode 100644
index 0000000000000..82c9fc27d8f29
--- /dev/null
+++ b/sci-mathematics/flint/files/flint-3.1.3_p1-fix-pc-location.patch
@@ -0,0 +1,26 @@
+From f4e0dfda90f6574048578f112bea1013d54f0987 Mon Sep 17 00:00:00 2001
+From: Michael Orlitzky <michael@orlitzky.com>
+Date: Sun, 10 Mar 2024 21:48:51 -0400
+Subject: [PATCH] CMakeLists.txt: install the pkg-config file to the configured
+ libdir
+
+Currently it installs to lib/pkgconfig, which can be incorrect on
+systems where (for example) the normal libdir is lib64 and "lib" is
+reserved for 32-bit libraries.
+---
+ CMakeLists.txt | 2 +-
+ 1 file changed, 1 insertion(+), 1 deletion(-)
+
+diff --git a/CMakeLists.txt b/CMakeLists.txt
+index 30935cef47..d8dfee38df 100644
+--- a/CMakeLists.txt
++++ b/CMakeLists.txt
+@@ -537,7 +537,7 @@ set(PACKAGE_NAME ${PROJECT_NAME})
+ set(PACKAGE_VERSION ${PROJECT_VERSION})
+ configure_file(flint.pc.in flint.pc @ONLY)
+ 
+-install(FILES ${CMAKE_CURRENT_BINARY_DIR}/flint.pc DESTINATION lib/pkgconfig)
++install(FILES ${CMAKE_CURRENT_BINARY_DIR}/flint.pc DESTINATION ${CMAKE_INSTALL_LIBDIR}/pkgconfig)
+ 
+ if(BUILD_TESTING)
+     set(FLINT_SRC ${CMAKE_CURRENT_SOURCE_DIR}/src) # To get src/test/main
diff --git a/sci-mathematics/flint/flint-3.1.3_p1.ebuild b/sci-mathematics/flint/flint-3.1.3_p1-r1.ebuild
similarity index 97%
rename from sci-mathematics/flint/flint-3.1.3_p1.ebuild
rename to sci-mathematics/flint/flint-3.1.3_p1-r1.ebuild
index 4f60961ecba29..bca7c62b7b66e 100644
--- a/sci-mathematics/flint/flint-3.1.3_p1.ebuild
+++ b/sci-mathematics/flint/flint-3.1.3_p1-r1.ebuild
@@ -48,6 +48,7 @@ DOCS="AUTHORS README.md doc/source/*.rst"
 PATCHES=(
 	"${FILESDIR}/flint-3.0.1-find-cblas.patch"
 	"${FILESDIR}/flint-3.1.3_p1-c99-I.patch"
+	"${FILESDIR}/flint-3.1.3_p1-fix-pc-location.patch"
 )
 
 src_configure() {