diff --git a/profiles/base/package.use.mask b/profiles/base/package.use.mask
index 90c9a78d9d48c..6bca4b6608f31 100644
--- a/profiles/base/package.use.mask
+++ b/profiles/base/package.use.mask
@@ -6,6 +6,12 @@
 # This file is only for generic masks. For arch-specific masks (i.e.
 # mask everywhere, unmask on arch/*) use arch/base.
 
+# Joonas Niilola <juippis@gentoo.org> (2022-05-03)
+# sndio is currently broken in Gentoo, #842420.
+# system-python is HIGHLY EXPERIMENTAL according to upstream, and
+# still being worked on in Gentoo.
+>=www-client/firefox-100.0 sndio system-python
+
 # Piotr Karbowski <slashbeast@gentoo.org> (2022-04-29)
 # There's a bug with gnutls support leading TLS certificates
 # validation failures on some certificates that are otherwise valid.