diff --git a/sci-mathematics/coq-serapi/Manifest b/sci-mathematics/coq-serapi/Manifest
index d5754b91dac08..61f749d719182 100644
--- a/sci-mathematics/coq-serapi/Manifest
+++ b/sci-mathematics/coq-serapi/Manifest
@@ -1,2 +1,3 @@
 DIST coq-serapi-0.15.0.tar.gz 268083 BLAKE2B aeea2cb8ed0f648f307715c464f2da90585718aa8afedf69b4e1c282265a12a3937044397787404e43286cebaaf1f48efde93d845cd71c1c97cc1b2e9a2a8835 SHA512 3ba1b63002d36a4c0e64f86170d31c4131dc02e8cb8573b39f03ed44d1e5f29c064c472bebad367b875b02e36ced6bfe8c5fb2023bd798b3b79f74a5a2f54189
 DIST coq-serapi-0.16.0.tar.gz 270647 BLAKE2B 8189e70bfa4208a613ec7a89d6fc72c15a9c1c29ed49cd53a561b72b4b9e55196bcb92d5e962309d8843036c30ec177588e2db7dd091443947b02e78f2df1880 SHA512 56cc74e9d2b1e13c7ffb94b32e206671ac904f6d7e633c830175eed6f7cb75a2b212be916316784dc7d697c6e5779e27ed402d5e7edbee8b7d84d2c533dc38c3
+DIST coq-serapi-0.16.1.tar.gz 271068 BLAKE2B 5e832f4b2d2627938f2399b3eff111a15987d7733e30ba6f6328dc0110631a1c42a212c5ed464037f8c521c11c46bf8bb8665bfdd93b5969949cdec584a42e18 SHA512 348a984897f99dd4f08a409251eaf50f792aa1fe96d71d5f895f3153c05131b2d6b15f10a18cf704e978676562547d0869a310e8d6969ffe69d5bdf1c212b756
diff --git a/sci-mathematics/coq-serapi/coq-serapi-0.16.1.ebuild b/sci-mathematics/coq-serapi/coq-serapi-0.16.1.ebuild
new file mode 100644
index 0000000000000..fed96a12b2dc7
--- /dev/null
+++ b/sci-mathematics/coq-serapi/coq-serapi-0.16.1.ebuild
@@ -0,0 +1,66 @@
+# Copyright 1999-2022 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+COQV=8.16.0
+
+inherit elisp-common dune
+
+DESCRIPTION="Serialization library and protocol for interaction with the Coq proof assistant"
+HOMEPAGE="https://github.com/ejgallego/coq-serapi/"
+# The tarball in SRC_URI is comprised of <supported coq>+<package version>
+SRC_URI="https://github.com/ejgallego/${PN}/archive/${COQV}+${PV}.tar.gz
+		-> ${P}.tar.gz"
+S="${WORKDIR}"/${PN}-${COQV}-${PV}
+
+LICENSE="GPL-3+"
+SLOT="0/${PV}"
+KEYWORDS="~amd64"
+IUSE="emacs +ocamlopt test"
+RESTRICT="!test? ( test )"
+
+RDEPEND="
+	>=sci-mathematics/coq-${COQV}:= <sci-mathematics/coq-8.17:=
+	>=dev-ml/ppx_sexp_conv-0.13.0:= <dev-ml/ppx_sexp_conv-0.15.0:=
+	dev-ml/cmdliner:=
+	dev-ml/ppx_compare:=
+	dev-ml/ppx_deriving:=
+	dev-ml/ppx_deriving_yojson:=
+	dev-ml/ppx_hash:=
+	dev-ml/ppx_import:=
+	dev-ml/sexplib:=
+	dev-ml/yojson:=
+"
+DEPEND="${RDEPEND}"
+BDEPEND="
+	emacs? ( >=app-editors/emacs-23.1:* )
+	test? ( sci-mathematics/coq-mathcomp )
+"
+
+PATCHES=( "${FILESDIR}"/${PN}-sertop.el-path.patch )
+SITEFILE="50sertop-gentoo.el"
+
+src_compile() {
+	dune_src_compile
+
+	use emacs && elisp-compile sertop.el
+}
+
+src_install() {
+	dune_src_install
+
+	rm -r "${D}"/usr/share/emacs || die
+	if use emacs ; then
+		elisp-install ${PN} sertop.el{,c}
+		elisp-site-file-install "${FILESDIR}/${SITEFILE}"
+	fi
+}
+
+pkg_postinst() {
+	use emacs && elisp-site-regen
+}
+
+pkg_postrm() {
+	use emacs && elisp-site-regen
+}