diff --git a/profiles/arch/arm64/package.use.mask b/profiles/arch/arm64/package.use.mask
index d96269bc0bff3..bb0f0109e084b 100644
--- a/profiles/arch/arm64/package.use.mask
+++ b/profiles/arch/arm64/package.use.mask
@@ -5,11 +5,10 @@
 # These are not currently supported on arm64. Porting wine-gecko and
 # wine-mono is on Wine's TODO[1], mingw64-toolchain lacks ebuild
 # support (crossdev might be usable, but users are on their own there),
-# dosbox is not keyworded here, and wow64 would require x86 emulation
-# to make sense.
+# and dosbox is not keyworded here.
 # [1] https://gitlab.winehq.org/wine/wine/-/wikis/ARM64#todo
-app-emulation/wine-vanilla crossdev-mingw dos gecko mingw mono wow64
-app-emulation/wine-staging crossdev-mingw dos gecko mingw mono wow64
+app-emulation/wine-vanilla crossdev-mingw dos gecko mingw mono
+app-emulation/wine-staging crossdev-mingw dos gecko mingw mono
 
 # NRK <nrk@disroot.org> (2025-03-17)
 # media-libs/libyuv is not keyworded