diff --git a/sys-cluster/ceph/ceph-16.2.8.ebuild b/sys-cluster/ceph/ceph-16.2.8.ebuild
index 56debbe477af9..4c0e1be4061eb 100644
--- a/sys-cluster/ceph/ceph-16.2.8.ebuild
+++ b/sys-cluster/ceph/ceph-16.2.8.ebuild
@@ -179,6 +179,7 @@ REQUIRED_USE="
 	mgr? ( cephfs )
 	rabbitmq? ( radosgw )
 	!system-boost? (
+		python_targets_python3_10
 		|| (
 			python_targets_python3_8
 			python_targets_python3_9