diff --git a/dev-util/meson/meson-0.48.2.ebuild b/dev-util/meson/meson-0.48.2.ebuild
index 8b2a97c795713..60e9ecb49c6c2 100644
--- a/dev-util/meson/meson-0.48.2.ebuild
+++ b/dev-util/meson/meson-0.48.2.ebuild
@@ -32,6 +32,11 @@ python_test() {
 		# test_cross_file_system_paths
 		unset XDG_DATA_HOME
 
+		# ASAN and sandbox both want to control LDPRELOAD
+		# https://bugs.gentoo.org/673016
+		export SANDBOX_ON=0
+		unset LD_PRELOAD
+
 		${EPYTHON} -u run_tests.py
 	) || die "Testing failed with ${EPYTHON}"
 }
diff --git a/dev-util/meson/meson-0.49.0.ebuild b/dev-util/meson/meson-0.49.0.ebuild
index d7d772117ac97..aa2b296613ec7 100644
--- a/dev-util/meson/meson-0.49.0.ebuild
+++ b/dev-util/meson/meson-0.49.0.ebuild
@@ -32,6 +32,11 @@ python_test() {
 		# test_cross_file_system_paths
 		unset XDG_DATA_HOME
 
+		# ASAN and sandbox both want to control LDPRELOAD
+		# https://bugs.gentoo.org/673016
+		export SANDBOX_ON=0
+		unset LD_PRELOAD
+
 		${EPYTHON} -u run_tests.py
 	) || die "Testing failed with ${EPYTHON}"
 }
diff --git a/dev-util/meson/meson-9999.ebuild b/dev-util/meson/meson-9999.ebuild
index d7d772117ac97..aa2b296613ec7 100644
--- a/dev-util/meson/meson-9999.ebuild
+++ b/dev-util/meson/meson-9999.ebuild
@@ -32,6 +32,11 @@ python_test() {
 		# test_cross_file_system_paths
 		unset XDG_DATA_HOME
 
+		# ASAN and sandbox both want to control LDPRELOAD
+		# https://bugs.gentoo.org/673016
+		export SANDBOX_ON=0
+		unset LD_PRELOAD
+
 		${EPYTHON} -u run_tests.py
 	) || die "Testing failed with ${EPYTHON}"
 }