diff --git a/media-libs/openexr/openexr-2.5.6.ebuild b/media-libs/openexr/openexr-2.5.6.ebuild
index afb333b3e1101..0583348afc4fc 100644
--- a/media-libs/openexr/openexr-2.5.6.ebuild
+++ b/media-libs/openexr/openexr-2.5.6.ebuild
@@ -13,7 +13,8 @@ S="${WORKDIR}/${P}/OpenEXR"
 
 LICENSE="BSD"
 SLOT="0/25" # based on SONAME
-KEYWORDS="amd64 ~arm arm64 ~ia64 ppc ppc64 sparc x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-solaris"
+# -ppc -sparc because broken on big endian, bug #818424
+KEYWORDS="amd64 ~arm arm64 ~ia64 -ppc ppc64 -sparc x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-solaris"
 IUSE="cpu_flags_x86_avx doc examples static-libs utils test"
 RESTRICT="!test? ( test )"
 
diff --git a/media-libs/openexr/openexr-2.5.7.ebuild b/media-libs/openexr/openexr-2.5.7.ebuild
index 6c2808911d812..990a17843d0df 100644
--- a/media-libs/openexr/openexr-2.5.7.ebuild
+++ b/media-libs/openexr/openexr-2.5.7.ebuild
@@ -13,7 +13,8 @@ S="${WORKDIR}/${P}/OpenEXR"
 
 LICENSE="BSD"
 SLOT="0/25" # based on SONAME
-KEYWORDS="amd64 ~arm arm64 ~ia64 ~ppc ~ppc64 ~riscv sparc x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-solaris"
+# -ppc -sparc because broken on big endian, bug #818424
+KEYWORDS="amd64 ~arm arm64 ~ia64 -ppc ~ppc64 ~riscv -sparc x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-solaris"
 IUSE="cpu_flags_x86_avx doc examples static-libs utils test"
 RESTRICT="!test? ( test )"
 
diff --git a/media-libs/openexr/openexr-3.0.5.ebuild b/media-libs/openexr/openexr-3.0.5.ebuild
index 242e04c954131..47c25d2cdfcaa 100644
--- a/media-libs/openexr/openexr-3.0.5.ebuild
+++ b/media-libs/openexr/openexr-3.0.5.ebuild
@@ -16,7 +16,8 @@ SRC_URI="https://github.com/AcademySoftwareFoundation/openexr/archive/refs/tags/
 LICENSE="BSD"
 SLOT="3/29" # based on SONAME
 # imath needs keywording: arm{,64}, hppa, ia64, ppc{,64}, sparc, x64-macos, x86-solaris
-KEYWORDS="~amd64 ~ia64 ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-solaris"
+# -ppc -sparc because broken on big endian, bug #818424
+KEYWORDS="~amd64 ~ia64 -ppc -sparc ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-solaris"
 IUSE="cpu_flags_x86_avx doc examples large-stack static-libs utils test threads"
 RESTRICT="!test? ( test )"
 
diff --git a/media-libs/openexr/openexr-3.1.1.ebuild b/media-libs/openexr/openexr-3.1.1.ebuild
index 48a92e0fed989..915f1405d3d7f 100644
--- a/media-libs/openexr/openexr-3.1.1.ebuild
+++ b/media-libs/openexr/openexr-3.1.1.ebuild
@@ -16,7 +16,8 @@ SRC_URI="https://github.com/AcademySoftwareFoundation/openexr/archive/refs/tags/
 LICENSE="BSD"
 SLOT="3/30" # based on SONAME
 # imath needs keywording: x64-macos, x86-solaris
-KEYWORDS="~amd64 ~arm ~arm64 ~ia64 ~ppc ~ppc64 ~sparc ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-solaris"
+# -ppc -sparc because broken on big endian, bug #818424
+KEYWORDS="~amd64 ~arm ~arm64 ~ia64 -ppc ~ppc64 -sparc ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-solaris"
 IUSE="cpu_flags_x86_avx doc examples large-stack static-libs utils test threads"
 RESTRICT="!test? ( test )"