diff --git a/dev-python/grpcio-tools/grpcio-tools-1.16.1.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.16.1.ebuild
index c6794ff397290..e91e65eac30e4 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.16.1.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.16.1.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_6 )
+PYTHON_COMPAT=( python3_6 )
 inherit distutils-r1
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.17.1.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.17.1.ebuild
index f51fd367c529f..045bea887550a 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.17.1.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.17.1.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_6 )
+PYTHON_COMPAT=( python3_6 )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.18.0.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.18.0.ebuild
index f51fd367c529f..045bea887550a 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.18.0.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.18.0.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_6 )
+PYTHON_COMPAT=( python3_6 )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.19.0.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.19.0.ebuild
index a70e95e026377..3627353b6a866 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.19.0.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.19.0.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_{6,7} )
+PYTHON_COMPAT=( python3_{6,7} )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.20.1.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.20.1.ebuild
index 5dba4c0666ea8..83f7c06e49e6a 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.20.1.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.20.1.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_{6,7} )
+PYTHON_COMPAT=( python3_{6,7} )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.21.1.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.21.1.ebuild
index 5dba4c0666ea8..83f7c06e49e6a 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.21.1.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.21.1.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_{6,7} )
+PYTHON_COMPAT=( python3_{6,7} )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.22.1.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.22.1.ebuild
index 6ee574d984425..97d026b22dd41 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.22.1.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.22.1.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_{6,7} )
+PYTHON_COMPAT=( python3_{6,7} )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.23.0.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.23.0.ebuild
index 6ee574d984425..97d026b22dd41 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.23.0.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.23.0.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_{6,7} )
+PYTHON_COMPAT=( python3_{6,7} )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.24.3.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.24.3.ebuild
index 6ee574d984425..97d026b22dd41 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.24.3.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.24.3.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_{6,7} )
+PYTHON_COMPAT=( python3_{6,7} )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"
diff --git a/dev-python/grpcio-tools/grpcio-tools-1.26.0.ebuild b/dev-python/grpcio-tools/grpcio-tools-1.26.0.ebuild
index aabe7f2b43cef..5f5084a83cac8 100644
--- a/dev-python/grpcio-tools/grpcio-tools-1.26.0.ebuild
+++ b/dev-python/grpcio-tools/grpcio-tools-1.26.0.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python2_7 python3_{6,7,8} )
+PYTHON_COMPAT=( python3_{6,7,8} )
 inherit distutils-r1 multiprocessing
 
 DESCRIPTION="Protobuf code generator for gRPC"