diff --git a/dev-python/py2neo/py2neo-3.1.2.ebuild b/dev-python/py2neo/py2neo-3.1.2.ebuild
index 6d1fc20736fe8..865ae1c8b842b 100644
--- a/dev-python/py2neo/py2neo-3.1.2.ebuild
+++ b/dev-python/py2neo/py2neo-3.1.2.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=6
 
-PYTHON_COMPAT=( python{2_7,3_5,3_6} pypy{,3} )
+PYTHON_COMPAT=( python3_{5,6} pypy3 )
 
 inherit distutils-r1
 
@@ -17,9 +17,3 @@ KEYWORDS="~amd64 ~x86"
 IUSE=""
 
 DEPEND="dev-python/setuptools[${PYTHON_USEDEP}]"
-
-python_compile() {
-	# https://github.com/nigelsmall/py2neo/issues/380
-	python_is_python3 || local -x CFLAGS="${CFLAGS} -fno-strict-aliasing"
-	distutils-r1_python_compile
-}