diff --git a/profiles/package.mask b/profiles/package.mask
index 1923d3e6f2895..e4be02d85c70d 100644
--- a/profiles/package.mask
+++ b/profiles/package.mask
@@ -32,6 +32,13 @@
 
 #--- END OF EXAMPLES ---
 
+# Sam James <sam@gentoo.org> (2021-02-10)
+# Causes circular dep with opam
+# seq -> opam-installer -> opam-format -> re -> seq
+# See ff101b42980416c2fdee330c105cabb745bc9a42
+# bug #769725
+=dev-ml/seq-1
+
 # Sergei Trofimovich <slyfox@gentoo.org> (2021-02-08)
 # Abandoned upstream. Was never ported from gtk-2.
 # A possible alternative is media-gfx/geeqie (gqview fork).