diff --git a/dev-python/virtualenvwrapper/virtualenvwrapper-4.7.1.ebuild b/dev-python/virtualenvwrapper/virtualenvwrapper-4.7.1.ebuild
index 7b6f6ecc11306..31d2569cf569b 100644
--- a/dev-python/virtualenvwrapper/virtualenvwrapper-4.7.1.ebuild
+++ b/dev-python/virtualenvwrapper/virtualenvwrapper-4.7.1.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=6
 
-PYTHON_COMPAT=( python{2_7,3_5} )
+PYTHON_COMPAT=( python3_5 )
 
 inherit distutils-r1
 
diff --git a/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.2-r1.ebuild b/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.2-r1.ebuild
index 976d371facf72..96cc47b78d447 100644
--- a/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.2-r1.ebuild
+++ b/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.2-r1.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python{2_7,3_5,3_6,3_7} )
+PYTHON_COMPAT=( python3_{5,6,7} )
 
 inherit distutils-r1
 
diff --git a/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.2.ebuild b/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.2.ebuild
index 35cc39469302a..fa6ba2fb1edba 100644
--- a/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.2.ebuild
+++ b/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.2.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=6
 
-PYTHON_COMPAT=( python{2_7,3_5,3_6} )
+PYTHON_COMPAT=( python3_{5,6} )
 
 inherit distutils-r1
 
diff --git a/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.4.ebuild b/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.4.ebuild
index 976d371facf72..96cc47b78d447 100644
--- a/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.4.ebuild
+++ b/dev-python/virtualenvwrapper/virtualenvwrapper-4.8.4.ebuild
@@ -3,7 +3,7 @@
 
 EAPI=7
 
-PYTHON_COMPAT=( python{2_7,3_5,3_6,3_7} )
+PYTHON_COMPAT=( python3_{5,6,7} )
 
 inherit distutils-r1