diff --git a/dev-python/pyopencl/pyopencl-2022.2.3.ebuild b/dev-python/pyopencl/pyopencl-2022.2.3.ebuild
index e966b7e97d340..253582817f5bf 100644
--- a/dev-python/pyopencl/pyopencl-2022.2.3.ebuild
+++ b/dev-python/pyopencl/pyopencl-2022.2.3.ebuild
@@ -18,6 +18,11 @@ SLOT="0"
 KEYWORDS="~amd64 ~ppc64"
 IUSE="examples opengl"
 
+# Running tests on GPUs requires both appropriate hardware and additional permissions
+# having been granted to the user running them. Testing on CPUs with dev-libs/pocl
+# is in theory possible but has been found to be very fragile, see e.g. Bug #872308.
+RESTRICT="test"
+
 COMMON=">=virtual/opencl-2"
 # libglvnd is only needed for the headers
 DEPEND="${COMMON}