diff --git a/dev-python/pymongo/Manifest b/dev-python/pymongo/Manifest
index 9b007d9eae425..be835a0daa2cf 100644
--- a/dev-python/pymongo/Manifest
+++ b/dev-python/pymongo/Manifest
@@ -1 +1,2 @@
 DIST mongo-python-driver-4.4.1.gh.tar.gz 1461820 BLAKE2B 42b2f5663bbc632205ebc1e979c6434122d797043cc545b3ff5b02956acd4d8d2b3a6b4a0308ca041fbb82aa3f530b305f4d21d42954c15b0c3ace3da6e1efd8 SHA512 fbdc6bd60eefbd554cadbea2173340e89e3cbec3377c97a592789750bb86ec68818d40f43b020c68023ff6c415bb4ceb36e7fb169d72b3e9c218880c6bfaf339
+DIST mongo-python-driver-4.5.0.gh.tar.gz 1481970 BLAKE2B fcb019042b6447093e1cfb9d66514954c31a26322060842b3c8e93d865f74db356004c6d7090d1a535d1ce523513cbd9e7935c7ee7655cdd47691d1b7ede97f0 SHA512 eb607f692c28daacef436e7649b3265465f8f785a68b29eda16b5ab5d926d0fa4737bcc6974f54778794dfd7fbcd95c30478867d6479ea45d412f2404cb2aa30
diff --git a/dev-python/pymongo/metadata.xml b/dev-python/pymongo/metadata.xml
index 49d5ee837cb88..dee6e50c5e665 100644
--- a/dev-python/pymongo/metadata.xml
+++ b/dev-python/pymongo/metadata.xml
@@ -9,10 +9,13 @@
 		<email>python@gentoo.org</email>
 		<name>Python</name>
 	</maintainer>
-	<longdescription lang="en">PyMongo is a Python distribution containing tools 
-	for working with MongoDB, and is the recommended way to work 
-	with MongoDB from Python.</longdescription>
+	<longdescription lang="en">
+		PyMongo is a Python distribution containing tools for working
+		with MongoDB, and is the recommended way to work with MongoDB
+		from Python.
+	</longdescription>
 	<use>
+		<flag name="native-extensions">Compiles native C extensions</flag>
 		<flag name="test-full">
 			Run test suite in full, including tests that run a local
 			database instance.
diff --git a/dev-python/pymongo/pymongo-4.5.0.ebuild b/dev-python/pymongo/pymongo-4.5.0.ebuild
new file mode 100644
index 0000000000000..0a82c759cf484
--- /dev/null
+++ b/dev-python/pymongo/pymongo-4.5.0.ebuild
@@ -0,0 +1,152 @@
+# Copyright 1999-2023 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+DISTUTILS_EXT=1
+DISTUTILS_USE_PEP517=setuptools
+PYTHON_COMPAT=( python3_{10..11} )
+
+inherit check-reqs distutils-r1
+
+MY_P=mongo-python-driver-${PV}
+DESCRIPTION="Python driver for MongoDB"
+HOMEPAGE="
+	https://github.com/mongodb/mongo-python-driver/
+	https://pypi.org/project/pymongo/
+"
+SRC_URI="
+	https://github.com/mongodb/mongo-python-driver/archive/${PV}.tar.gz
+		-> ${MY_P}.gh.tar.gz
+"
+S=${WORKDIR}/${MY_P}
+
+LICENSE="Apache-2.0"
+SLOT="0"
+KEYWORDS="~amd64 ~arm ~arm64 ~hppa ~ppc ~ppc64 ~riscv ~s390 ~sparc ~x86"
+IUSE="doc kerberos +native-extensions +test-full"
+
+RDEPEND="
+	<dev-python/dnspython-3.0.0[${PYTHON_USEDEP}]
+	kerberos? ( dev-python/kerberos[${PYTHON_USEDEP}] )
+"
+BDEPEND="
+	test? (
+		test-full? (
+			>=dev-db/mongodb-2.6.0
+		)
+	)
+"
+
+distutils_enable_sphinx doc
+distutils_enable_tests unittest
+
+reqcheck() {
+	if use test && use test-full; then
+		# During the tests, database size reaches 1.5G.
+		local CHECKREQS_DISK_BUILD=1536M
+
+		check-reqs_${1}
+	fi
+}
+
+pkg_pretend() {
+	reqcheck pkg_pretend
+}
+
+pkg_setup() {
+	reqcheck pkg_setup
+}
+
+python_compile() {
+	# causes build errors to be fatal
+	local -x TOX_ENV_NAME=whatever
+	local DISTUTILS_ARGS=()
+	# unconditionally implicitly disabled on pypy3
+	if ! use native-extensions; then
+		DISTUTILS_ARGS+=( --no_ext )
+	fi
+
+	distutils-r1_python_compile
+}
+
+python_test() {
+	rm -rf bson pymongo || die
+
+	local -x PYTEST_DISABLE_PLUGIN_AUTOLOAD=1
+	local EPYTEST_DESELECT=(
+		# network-sandbox
+		test/test_client.py::ClientUnitTest::test_connection_timeout_ms_propagates_to_DNS_resolver
+		test/test_client.py::TestClient::test_service_name_from_kwargs
+		test/test_client.py::TestClient::test_srv_max_hosts_kwarg
+		test/test_dns.py::TestCaseInsensitive::test_connect_case_insensitive
+		test/test_srv_polling.py
+		test/test_uri_spec.py::TestAllScenarios::test_test_uri_options_srv-options_SRV_URI_with_custom_srvServiceName
+		test/test_uri_spec.py::TestAllScenarios::test_test_uri_options_srv-options_SRV_URI_with_invalid_type_for_srvMaxHosts
+		test/test_uri_spec.py::TestAllScenarios::test_test_uri_options_srv-options_SRV_URI_with_negative_integer_for_srvMaxHosts
+		test/test_uri_spec.py::TestAllScenarios::test_test_uri_options_srv-options_SRV_URI_with_positive_srvMaxHosts_and_loadBalanced=fa
+		test/test_uri_spec.py::TestAllScenarios::test_test_uri_options_srv-options_SRV_URI_with_srvMaxHosts
+		test/test_uri_spec.py::TestAllScenarios::test_test_uri_options_srv-options_SRV_URI_with_srvMaxHosts=0_and_loadBalanced=true
+		test/test_uri_spec.py::TestAllScenarios::test_test_uri_options_srv-options_SRV_URI_with_srvMaxHosts=0_and_replicaSet
+
+		# broken regularly by changes in mypy
+		test/test_typing.py::TestMypyFails::test_mypy_failures
+	)
+
+	if ! use test-full; then
+		# .invalid is guaranteed to return NXDOMAIN per RFC 6761
+		local -x DB_IP=mongodb.invalid
+		epytest
+		return
+	fi
+
+	# Yes, we need TCP/IP for that...
+	local -x DB_IP=127.0.0.1
+	local -x DB_PORT=27000
+
+	local dbpath=${TMPDIR}/mongo.db
+	local logpath=${TMPDIR}/mongod.log
+
+	# Now, the hard part: we need to find a free port for mongod.
+	# We're just trying to run it random port numbers and check the log
+	# for bind errors. It shall be noted that 'mongod --fork' does not
+	# return failure when it fails to bind.
+
+	mkdir -p "${dbpath}" || die
+	while true; do
+		ebegin "Trying to start mongod on port ${DB_PORT}"
+
+		LC_ALL=C \
+		mongod --dbpath "${dbpath}" --nojournal \
+			--bind_ip ${DB_IP} --port ${DB_PORT} \
+			--unixSocketPrefix "${TMPDIR}" \
+			--logpath "${logpath}" --fork \
+		&& sleep 2
+
+		# Now we need to check if the server actually started...
+		if [[ ${?} -eq 0 && -S "${TMPDIR}"/mongodb-${DB_PORT}.sock ]]; then
+			# yay!
+			eend 0
+			break
+		elif grep -q 'Address already in use' "${logpath}"; then
+			# ay, someone took our port!
+			eend 1
+			: $(( DB_PORT += 1 ))
+			continue
+		else
+			eend 1
+			eerror "Unable to start mongod for tests. See the server log:"
+			eerror "	${logpath}"
+			die "Unable to start mongod for tests."
+		fi
+	done
+
+	local failed
+	nonfatal epytest || failed=1
+
+	mongod --dbpath "${dbpath}" --shutdown || die
+
+	[[ ${failed} ]] && die "Tests fail with ${EPYTHON}"
+
+	rm -rf "${dbpath}" || die
+}